A novel benzothiazole-based cryptand was designed and synthesized, and it exhibited high fluorescence intensity in the presence of Zn ions based on the metal chelation inhibition of the excited state intramolecular proton transfer (ESIPT) process. The structure of the cryptand was confirmed by NMR, mass spectroscopy and X-ray crystallography. Importantly, this probe showed high selectivity over other biologically relevant metal ions and anions and a detection limit of 0.20 μM, which is acceptable within the EPA (US) limit.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c9dt00548j | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Metabolites profile, DPPH and ABTS scavenging and myoglobin protection ratio of aqueous infusion and methanolic extracts of Mexican Lippia alba.
Food Chem
March 2025
Doctorado en Sustentabilidad, Universidad Autónoma de Occidente, Unidad Regional Guasave, Av. Universidad S/N, Fraccionamiento Villa Universidad, C.P, 81048 Guasave, Sinaloa, Mexico; Departamento de Salud-Licenciatura en Ciencias Biomédicas, Universidad Autónoma de Occidente, Unidad Regional Guasave, Av. Universidad S/N, Fraccionamiento Villa Universidad, C.P, 81048 Guasave, Sinaloa, Mexico. Electronic address:
Lippia alba is a medicinal plant widely used by the inhabitants of northwest Mexico to relieve gastrointestinal and inflammatory problems; however, the phytochemical profile and bioactive potential of their polar fraction have been poorly studied. In this study phytochemical screening showed qualitatively the presence of phenolic compounds, tannins, and triterpenes in L. alba aqueous infusion and stem, flower, and leaves methanolic extracts.
View Article and Find Full Text PDFBenzothiadiazole-Fused Cyanoindone: A Superior Building Block for Designing Ultra-Narrow Bandgap Electron Acceptor with Long-Range Ordered Stacking.
Angew Chem Int Ed Engl
November 2024
State Key Laboratory of Silicon and Advanced Semiconductor Materials, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310058, China.
There are great demands of developing ultra-narrow bandgap electron acceptors for multifunctional electronic devices, particularly semi-transparent organic photovoltaics (OPVs) for building-integrated applications. However, current ultra-narrow bandgap materials applied in OPVs, primarily based on electron-rich cores, exhibit defects of high-lying energy levels and inferior performance. We herein proposed a novel strategy by designing the benzothiazole-fused cyanoindone (BTC) unit with ultra-strong electron-withdrawing ability as the terminal to synthesize the acceptor BTC-2.
View Article and Find Full Text PDFHepatitis B Virus X Protein Induces Reactive Oxygen Species Generation via Activation of p53 in Human Hepatoma Cells.
Biomolecules
September 2024
Department of Integrated Biological Science, The Graduate School, Pusan National University, Busan 46241, Republic of Korea.
Hepatitis B virus (HBV), particularly through the HBx protein, induces oxidative stress during liver infections. This study reveals that HBx increases reactive oxygen species (ROS) via two distinct mechanisms. The first mechanism is p53-independent, likely involving mitochondrial dysfunction, as demonstrated by elevated ROS levels in p53-deficient Hep3B cells and p53-knocked-down HepG2 cells after HBx expression or HBV infection.
View Article and Find Full Text PDFThe potential of supramolecular synthon to develop coamorphous systems with tailored physical stability: Mechanistic insights integrating kinetics and thermodynamics.
Int J Pharm
December 2024
School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, PR China. Electronic address:
Coamorphous drug delivery systems have received increasing interest owing to their potential to improve the solubility, dissolution and bioavailability of poorly water-soluble drugs. However, the crystallization risk is one of major limitations in their application. It has been widely recognized that the coformer plays a vital role in physical stability of coamorphous formulation.
View Article and Find Full Text PDFEcological linkages between top-down designed benzothiazole-degrading consortia and selection strength: From performance to community structure and functional genes.
Water Res
December 2024
State Key Laboratory of Pollution Control and Resource Reuse, School of Environment, Nanjing University, Nanjing 210023, China. Electronic address:
Article Synopsis
- The biodegradation of nitrogenous heterocyclic compounds (NHCs) like benzothiazole presents environmental challenges due to inefficient breakdown processes.
- Research revealed that varying the concentration of benzothiazole impacts the structure and efficiency of microbial consortia, with higher concentrations favoring Rhodococcus, which is particularly effective at degrading these compounds.
- Understanding the interactions between different microbial species and their response to selection pressure helps in designing more effective synthetic microbiomes for environmental cleanup.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!