Hypocalcemia is a potentially fatal electrolyte imbalance with complications that include seizures, tetany, prolonged QT interval, cardiomyopathy, and congestive heart failure. In chi dren, persistent hypocalcemia can also be detrimental to bone growth and health. Therefore, it is important to recognize the many ways this electrolyte imbalance may present and determine its etiology. This article provides a framework for assessing hypocalcemia and describes in detail a case with a rare cause of refractory hypocalcemia. [Pediatr Ann. 2019;48(5):e208-e211.].
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http://dx.doi.org/10.3928/19382359-20190423-01 | DOI Listing |
J Pediatr Genet
December 2024
Centre for Human Genetics, Bengaluru, Karnataka, India.
Neuronal ceroid lipofuscinosis-type 1 (NCL-1) is a neurodegenerative lysosomal storage disorder. Vitamin D-dependent rickets type 1 (VDDR-1) is a rare cause of refractory rickets. Here, we report an unusual association of NCL-1 with VDDR-1.
View Article and Find Full Text PDFCureus
October 2024
Department of Endocrinology Diabetes Medicine, Samatvam Diabetes Endocrinology and Medical Center Samatvam: Science and Research for Human Welfare Trust, Bangalore, IND.
Parathyroid carcinoma (PC) is a rare malignancy. In January 2022, a 41-year-old woman presented with weight loss, proximal muscle weakness, and bone pain. She was diagnosed with severe hypercalcemia with serum calcium of 15.
View Article and Find Full Text PDFCureus
September 2024
Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, USA.
Obesity poses a global health challenge with significant individual and societal impacts. Bariatric surgery, including Roux-en-Y gastric bypass (RYGB) and biliopancreatic diversion/duodenal switch (BPD/DS), is effective for long-term weight management but can lead to serious nutritional deficiencies, particularly hypocalcemia. This report presents the rare case of a 35-year-old woman with severe, recurrent hypocalcemia following BPD/DS surgery, complicated by iatrogenic hypoparathyroidism from prior thyroidectomy.
View Article and Find Full Text PDFJAMA
November 2024
Division of Nephrology, University of Washington School of Medicine, Seattle.
Case Rep Endocrinol
September 2024
Department of Medicine Lewis Katz School of Medicine Temple University, Philadelphia, Pennsylvania, USA.
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