AI Article Synopsis
- The study aimed to compare the enzyme activity of different papain solutions to validate in-house preparations.
- Two types of in-house papain solutions were compared with a commercial solution using samples of weak RhD red cells.
- Results indicated that the in-house solutions had similar enzyme reactivity to the commercial one, demonstrating economic benefits and potential for inclusion in routine immunohematological practices.
Article Abstract
Objective: To compare the enzyme activity of different presentations of papain solution to validate in-house preparations.
Methods: Two papain solutions were prepared, and the third presentation was a commercial solution. Tests were carried out with samples of red cells typed as weak RhD.
Results: In-house prepared papain solutions showed similar enzyme reactivity, and statistically no differences compared to the enzyme activity of the commercial solution.
Conclusion: Evaluating the cost-benefit ratio, the in-house prepared papain solutions present more economic advantages, and can be incorporated into immunohematological routines as a way to cope with periods of financial crisis and cost-containment policies.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497125 | PMC |
| http://dx.doi.org/10.31744/einstein_journal/2019AO4328 | DOI Listing |
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