Background: The wave represents ECG repolarization, whose detection is required during myocardial ischemia, and the first significant change in the ECG signal is being observed in the ST segment followed by changes in other waves like wave and QRS complex. To offer guidance in clinical diagnosis, decision-making, and daily mobile ECG monitoring, the wave needs to be detected firstly. Recently, the sliding area-based method has received an increasing amount of attention due to its robustness and low computational burden. However, the parameter setting of the search window's boundaries in this method is not adaptive. Therefore, in this study, we proposed an improved sliding window area method with more adaptive parameter setting for wave detection.
Methods: Firstly, -means clustering was used in the annotated MIT QT database to generate three piecewise functions for delineating the relationship between the RR interval and the interval from the peak to the wave onset and that between the RR interval and the interval from the peak to the wave offset. Then, the grid search technique combined with 5-fold cross validation was used to select the suitable parameters' combination for the sliding window area method.
Results: With respect to onset detection in the QT database, 1 improved from 54.70% to 70.46% and 54.05% to 72.94% for the first and second electrocardiogram (ECG) channels, respectively. For offset detection, 1 also improved in both channels as it did in the European ST-T database.
Conclusions: 1 results from the improved algorithm version were higher than those from the traditional method, indicating a potentially useful application for the proposed method in ECG monitoring.
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http://dx.doi.org/10.1155/2019/3130527 | DOI Listing |
BMC Bioinformatics
January 2025
Centre for Big Data Research in Health, University of New South Wales, Sydney, Australia.
Background: Due to the complexity and cost of preparing histopathological slides, deep learning-based methods have been developed to generate high-quality histological images. However, existing approaches primarily focus on spatial domain information, neglecting the periodic information in the frequency domain and the complementary relationship between the two domains. In this paper, we proposed a generative adversarial network that employs a cross-attention mechanism to extract and fuse features across spatial and frequency domains.
View Article and Find Full Text PDFRev Cardiovasc Med
January 2025
Cardiology Department, Université de Mons, 7000 Mons, Belgium.
Background: Neuromodulation has been shown to increase the efficacy of atrial fibrillation (AF) ablation procedures. However, despite its ability to influence the autonomic nervous system (ANS), the exact mechanism of action remains unclear. The activity of the ANS via the intracardiac nervous system (ICNS) can be inferred from heart rate variability (HRV).
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Department of Molecular Medicine and Surgery, Karolinska Institutet, 17176 Stockholm, Sweden.
A previous genome-wide association study (GWAS) in colorectal cancer (CRC) patients with gastric and/or prostate cancer in their families suggested genetic loci with a shared risk for these three cancers. A second haplotype GWAS was undertaken in the same colorectal cancer patients and different controls with the aim of confirming the result and finding novel loci. The haplotype GWAS analysis involved 685 patients with colorectal cancer cases and 1642 healthy controls from Sweden.
View Article and Find Full Text PDFPLoS One
January 2025
Faculty of Engineering, Free University of Bozen-Bolzano, Bolzano, South Tyrol, Italy.
Appraisal models, such as the Scherer's Component Process Model (CPM), represent an elegant framework for the interpretation of emotion processes, advocating for computational models that capture emotion dynamics. Today's emotion recognition research, however, typically classifies discrete qualities or categorised dimensions, neglecting the dynamic nature of emotional processes and thus limiting interpretability based on appraisal theory. In our research, we estimate emotion intensity from multiple physiological features associated to the CPM's neurophysiological component using dynamical models with the aim of bringing insights into the relationship between physiological dynamics and perceived emotion intensity.
View Article and Find Full Text PDFEntropy (Basel)
January 2025
School of Software Engineering, Xi'an Jiaotong University, Xi'an 710049, China.
Non-stationary multi-armed bandit (MAB) problems have recently attracted extensive attention. We focus on the abruptly changing scenario where reward distributions remain constant for a certain period and change at unknown time steps. Although Thompson sampling (TS) has shown success in non-stationary settings, there is currently no regret bound analysis for TS with uninformative priors.
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