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Assessing Obstetrics and Gynecology (OBGYN) Clinicians' Knowledge, Practice, and Attitudes toward Anorexia Nervosa, Atypical Anorexia Nervosa, and Amenorrhea.
J Pediatr Adolesc Gynecol
December 2024
Penn State College of Medicine, Hershey, PA, USA; Division of Adolescent Medicine.
Study Objective: Anorexia nervosa (AN) and atypical anorexia nervosa (AAN) are eating disorders (EDs) characterized by extreme restriction of energy intake. However, in contrast to AN, those with AAN are not underweight. Although individuals with either AN or AAN can experience associated functional hypothalamic amenorrhea (FHA) that may prompt them to seek gynecological care, little is known about OBGYNs' knowledge and approach to these patients; this study sought to fill this gap.
View Article and Find Full Text PDFNovel variant alters splicing of in family with features of Loeys-Dietz syndrome.
Front Genet
December 2024
HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States.
Loeys-Dietz syndrome (LDS) is a connective tissue disorder representing a wide spectrum of phenotypes, ranging from isolated thoracic aortic aneurysm or dissection to a more severe syndromic presentation with multisystemic involvement. Significant clinical variability has been noted for both related and unrelated individuals with the same pathogenic variant. We report a family of five affected individuals with notable phenotypic variability who appear to have two distinct molecular causes of LDS, one attributable to a missense variant in and the other an intronic variant 6 bp upstream from a splice junction in .
View Article and Find Full Text PDFDigital upgrade of drainage detention devices for forced retention.
J Environ Manage
December 2024
Department of Infrastructure and Water Management, Faculty of Civil and Environmental Engineering and Architecture, Rzeszow University of Technology, Ave Powstańców Warszawy 6, 35-959, Rzeszów, Poland. Electronic address:
Current urban challenges related to local urban flooding require effective preventive measures. This applies particularly to various methods of stormwater retention, including forced retention, and solutions that enable cooperation between small individual retention systems and drainage systems. Therefore, this study presents the results of research on the hydraulic efficiency of controllable systems, which combine the features of an on-site tank with the solutions of network tanks to increase the retention of stormwater in drainage systems.
View Article and Find Full Text PDFUncovering the complexity of source mechanism in an anisotropic coal mine using sequential inversion.
Sci Rep
December 2024
Department of Geophysics, Graduate School of Science, Tohoku University, Sendai, 980-8578, Japan.
Accurate characterisation of seismic source mechanisms in mining environments is crucial for effective hazard mitigation, but it is complicated by the presence of anisotropic geological conditions. Neglecting anisotropic effects during moment tensor (MT) inversion introduces significant distortions in the retrieved source characteristics. In this study, we investigated the impact of ignoring anisotropy during MT inversion on the reliability of hazard assessment.
View Article and Find Full Text PDFVenom from Spiders Collected in Southeastern and Northeastern Brazilian Regions Cause Hemotoxic Effects on Human Blood Components.
Toxins (Basel)
December 2024
Molecular Toxinology Lab, Research and Development Department, Ezequiel Dias Foundation-FUNED, Belo Horizonte 30510-010, MG, Brazil.
Spiders of the genus represent a public health problem in Brazil due to the severity of the cutaneous and systemic effects that may result from their bite. In the systemic form of loxoscelism, hemolytic anemia, thrombocytopenia, and disseminated intravascular coagulation can occur. Despite the seriousness of accidents, the venom of some species has not yet been properly characterized considering these hemotoxic effects, such as that of , , and .
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