AI Article Synopsis
- - Brown adipose tissue (BAT) could help prevent lifestyle-related diseases, and this study investigates the use of near-infrared time-resolved spectroscopy (NIR) to measure human BAT density (BAT-d).
- - Key parameters measured by NIR include total hemoglobin, oxygenated hemoglobin, deoxygenated hemoglobin, and reduced scattering coefficient, specifically in the supraclavicular region where BAT is found.
- - Results indicate that total hemoglobin and oxygenated hemoglobin levels increase in winter compared to summer and are associated with cold-induced thermogenesis, suggesting NIR is an effective, quick, and non-invasive way to assess BAT density.
Article Abstract
Brown adipose tissue (BAT) may potentially be used in strategies for preventing lifestyle-related diseases. We examine evidence that near-infrared time-resolved spectroscopy (NIR) is capable of estimating human BAT density (BAT-d). The parameters examined in this study are total hemoglobin [total-Hb], oxygenated Hb [oxy-Hb], deoxygenated Hb [deoxy-Hb], Hb O saturation (StO), and the reduced scattering coefficient in the supraclavicular region (μ'), where BAT deposits can be located; corresponding parameters in the control deltoid region are obtained as controls. Among the NIR parameters, [total-Hb] and [oxy-Hb] show region-specific increases in winter, compared to summer. Further, [total-Hb] and [oxy-Hb] are correlated with cold-induced thermogenesis in the supraclavicular region. We conclude that NIR-determined [total-Hb] and [oxy-Hb] are useful parameters for evaluating BAT-d in a simple, rapid, non-invasive manner.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539985 | PMC |
| http://dx.doi.org/10.3390/ijms20092214 | DOI Listing |
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