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Prediction of axillary lymph node metastasis in breast cancer patients based on ultrasonograhic-clinicopathologic features.
Pak J Med Sci
January 2025
M. Jawaid A. Mallick, MD Consultant Oncologist, Head of Department of Oncology, Dr. Ziauddin Hospital, Karachi, Pakistan.
Background & Objective: Determination of axillary lymph-node status plays a pivotal role in decision making for breast cancer treatment. Biopsy is the current standard of care but hold risks of complications as well. We aimed to find out the correlation of sonographic features of lymph node and histo-pathological findings, to predict axillary lymph-node metastasis in breast cancer patients.
View Article and Find Full Text PDFLiver fibrosis classification on trichrome histology slides using weakly supervised learning in children and young adults.
J Pathol Inform
January 2025
Cincinnati Children's AI Imaging Research (CAIIR) Center, Cincinnati, OH, United States.
Background: Traditional liver fibrosis staging via percutaneous biopsy suffers from sampling bias and variable inter-pathologist agreement, highlighting the need for more objective techniques. Deep learning models for disease staging from medical images have shown potential to decrease diagnostic variability, with recent weakly supervised learning strategies showing promising results even with limited manual annotation.
Purpose: To study the clustering-constrained attention multiple instance learning (CLAM) approach for staging liver fibrosis on trichrome whole slide images (WSIs) of children and young adults.
Partial directed coherence analysis of resting-state EEG signals for alcohol use disorder detection using machine learning.
Front Neurosci
January 2025
Center of Excellence in Intelligent Engineering Systems (CEIES), Department of Electrical and Computer Engineering, Faculty of Engineering, King Abdulaziz University, Jeddah, Saudi Arabia.
Introduction: Excessive alcohol consumption negatively impacts physical and psychiatric health, lifestyle, and societal interactions. Chronic alcohol abuse alters brain structure, leading to alcohol use disorder (AUD), a condition requiring early diagnosis for effective management. Current diagnostic methods, primarily reliant on subjective questionnaires, could benefit from objective measures.
View Article and Find Full Text PDFThe "Triangle" Sign: A Novel Ultrasound Marker for Diagnosing Total Choroidal Detachment and Total Suprachoroidal Hemorrhage.
Clin Ophthalmol
January 2025
University Eye Clinic Maastricht, Maastricht, the Netherlands.
Purpose: This study aims to explore the diagnostic utility of ultrasound B-scan while introducing the "Triangle" sign as a novel indicator. It also validates the sign's efficacy in distinguishing between choroidal detachment (CD) and suprachoroidal hemorrhage (SCH) from retinal detachment (RD) and vitreous hemorrhage (VH).
Patients And Methods: Retrospective analysis of consecutive cases of total CD and SCH undergoing B-scan at a single tertiary imaging center.
Background Incidental gallbladder carcinoma (IGBC) remains a significant clinical challenge, with its diagnosis often delayed due to the asymptomatic nature of the disease and its incidental discovery post-cholecystectomy. This study's aim is to calculate incidence in a high-risk, region-specific (North Indian) population and also to provide novel insights into clinical presentation as well as macroscopic and histopathological features of IGBC. Material and methods This retrospective observational study spanned four years (August 2013 to July 2016) and included a total of 3096 cases.
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