Purpose: It can be extremely challenging to replace a hopeless tooth in the maxillary central incisor area with an implant restoration, especially when the bony housing of the tooth is severely damaged. This condition is frequently found in teeth that have been severely traumatized in childhood. To avoid their extraction, these teeth might have been exposed to multiple compromised treatments and repeated traumatic injuries. When skeletal changes cease and implant therapy becomes an option, the surgeon may often find only remnants of the socket walls. This imposes difficulty when regenerating the missing tissues required for long-term functional and esthetic implant restoration. This article describes the unique anatomical, biological, and surgical considerations in the treatment of such a case.
Materials And Methods: In the reconstruction of a safe bony housing around the implant, obliteration of the incisive canal was followed by the use of bovine bone mineral (BBM) and titanium mesh (Ti-mesh) layered with a crosslinked collagen membrane. The soft tissue was augmented with a xenogeneic soft tissue matrix and further enhanced by a novel technique, the 'radial cuts technique.'
Results: Functional and esthetic implant restoration was successfully achieved. Follow-up of the patient took place for 2 years post-implant loading and 3 years post-ridge augmentation, after which the stability of the implant and surrounding tissue was demonstrated.
Conclusion: Enhanced functional and esthetic results may be achieved when BBM and Ti-mesh layered with a soft collagen membrane are utilized as augmentation materials in the esthetic zone. The key factors for success in this case were combining the advantages of the different materials with a carefully considered sequence of procedures.
Download full-text PDF |
Source |
---|
Int J Biol Macromol
January 2025
Institute for Special Environmental Biophysics, Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an 710100, Shaanxi, PR China; Research & Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen 518063, PR China. Electronic address:
Magnetic nanoparticles effectively target drug delivery, contrast agents, biosensors, and more. Urchin-like magnetic nanoparticles (UMN) with abundant spike-like structures exhibit superior magneto-mechanical force to destroy tumor cells compared with other shapes of magnetic nanoparticles. However, when cell contents are released from tumor cells induced by magneto-mechanical force, they can act on surrounding tumor cells to facilitate tumor development.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
College of Chemistry and Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, China. Electronic address:
A vast sum of fish waste is being annually discarded by marine fishing industries imposing serious environmental pollution concerns. However, these aquatic discarded matters are captivating sources of collagen, a fibrous protein with eminent social and economic relevance. Collagen is conventionally recovered using outdated complex processes requiring many reagents, multiple steps, and extended periods.
View Article and Find Full Text PDFExp Eye Res
January 2025
Department of Ophthalmology, Zhongshan Hospital, Fudan University, Shanghai, China. Electronic address:
The study aimed to compare the effects of different types of excimer laser keratectomy on rabbit corneas and to identify the optimal disease model for corneal ectasia. Additionally, investigating the structural and molecular alterations in the novel disease model helped explore the mechanisms underlying biomechanical cues in corneal ectasia. 2.
View Article and Find Full Text PDFInflamm Res
January 2025
Department of Burns and Cutaneous Surgery, Xijing Hospital, Air Force Medical University, No.127 Changle West Road, Xincheng District, Xi'an, 710032, Shaanxi, China.
Background: Hypertrophic scar (HS) is a severe skin fibrosis. Transplanting stem cells carrying anti-fibrotic cytokine genes, like interferon-gamma (IFN-γ), is a novel therapeutic strategy. Human amniotic epithelial cells (hAECs) are ideal seed cells and gene vectors.
View Article and Find Full Text PDFMolecules
January 2025
Grupo Biomateriales Dentales, Escuela de Odontología, Universidad del Valle, Calle 4B # 36-00, Cali 760001, Colombia.
Scaffolds for regenerative therapy can be made from natural or synthetic polymers, each offering distinct benefits. Natural biopolymers like chitosan (CS) are biocompatible and biodegradable, supporting cell interactions, but lack mechanical strength. Synthetic polymers like polyvinyl alcohol (PVA) provide superior mechanical strength and cost efficiency but are not biodegradable or supportive of cell adhesion.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!