AI Article Synopsis

  • - The study investigates how perinatal depression impacts the socioemotional development of children, as this form of depression can lead to negative developmental outcomes during the early years of a child's life.
  • - 1154 pregnant women from a rural area in Pakistan were recruited between 2014 and 2016, with ongoing assessments of maternal mental health and child development at multiple time points (3, 6, 12, 24, and 36 months).
  • - Future plans include tracking these mother-child pairs up to ages 7-8 years, incorporating school experiences, and continuing to assess the influence of maternal depression on child development.

Article Abstract

Purpose: This is a prospective pregnancy-birth cohort designed to investigate the effects of depression on socioemotional development of children. Perinatal depression is a risk factor for poor child development and for many it has a recurring chronic course. Thus, the exposure to depression can continue through the early years of the child with detrimental developmental outcomes.

Participants: Between October 2014 and February 2016, we recruited 1154 pregnant women from a rural subdistrict of Pakistan. Data include longitudinal and repeated measures of maternal psychosocial measures and child growth, cognitive and socioemotional measures. Follow-up include mother-child dyad assessments at 3rd, 6th, 12th, 24th and 36th months of child age. All these follow-ups are community based at the household level. We have competed baseline assessment.

Findings To Date: Of the eligible dyads, we followed 885 (76.6%), 929 (91%) and 940 (93.3%) at 3, 6 and 12 months post-childbirth. We include a subsample mother-child dyad DNA and inflammatory biomarkers, 73 and 104, respectively.

Future Plans: While we continue to do 24-month and 36-month follow-up assessments, we plan to follow these mother-child dyads up to the age of 7-8 years with some children being exposed to at least 1 year of school environment. Investigators interested in learning more about the study can contact (jmaselko@unc.edu) and (siham.sikander@hdrfoundation.org).

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502044PMC
http://dx.doi.org/10.1136/bmjopen-2018-025644DOI Listing

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