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Anti- Activity of Egyptian Herbal Extracts (Family: Asteraceae) with Emphasis on . | LitMetric
(Forssk.) Sch. Bip. (known as Qaysoom), L. (known as Shoak Elgamal) and L.(known Shih Baladi) are members of the Asteraceae family known for their traditional medical use in Egypt. The ethanol extracts of these plants were evaluated for their efficacy against a protozoan parasite (). Two different molecular subtypes of were used (ST1 and ST3). Significant growth inhibition of was observed when exposed to both (99.3%) and (95.6%) with minimal inhibitory concentration (MIC) at 2000 µg/mL. Under the effect of the extracts, changes in morphology were noted, with the complete destruction of forms after 72 h with the dose of 4000 µg/mL. Different subtypes displayed different responses to the herbal extracts tested. ST1 exhibited significantly different responses to the herbal extracts compared to ST3. was selected as the herb of choice considering all of its variables and because of its effective action against . It was then exposed to further fractionation and observation of its effect on ST1 and ST3. Solvent portioned fractions (dichloromethane (DCM), ethyl acetate (EtOAc) and n-hexane) in were found to be the potent active fractions against both of the subtypes used.
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