Primary sino-nasal neuroendocrine carcinomas (PSNNECs) are rare, with a wide spectrum of histological differentiation. Advanced tumors may invade the surrounding structures, such as the skull base, orbit, or brain. Here, we present a rare case of PSNNEC and its management by concurrent chemoradiation (CCRT) followed by adjuvant chemotherapy with the radiological resolution of the tumor mass.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488343PMC
http://dx.doi.org/10.7759/cureus.4144DOI Listing

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