Background: The current study aimed to contribute to the understanding of the session to session relationship between craving and drinking during the course of treatment via the incorporation into the analysis of both a) motivation to avoid alcohol and 2) pretreatment change, given that half of all individuals entering treatment change their drinking prior to the first session.
Methods: Sixty-three treatment-seeking participants received 12 weeks of CBT for alcohol dependence and completed assessments of approach inclinations, avoidance inclinations and drinking behaviors at the end of each session.
Results: Consistent with our hypothesis, motivations to avoid alcohol and pretreatment change significantly interacted with craving to predict both number of drinking days and heavy drinking days during the interval between sessions. Specifically, among lower pretreatment changers, motivation to avoid alcohol moderated the effect of craving on number of drinking days and number of heavy drinking days, such that craving positively predicted drinking among those lower on motivations to avoid only. In contrast, among higher pretreatment changers, cravings positively predicted drinking among those higher on motivations to avoid alcohol.
Conclusions: These findings highlight the importance of measuring both desire to consume and desire to avoid consuming alcohol simultaneously, and suggest that ambivalence may function differently depending on whether one is initiating (low pretreatment change) versus maintaining change (high pretreatment change).
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http://dx.doi.org/10.1016/j.drugalcdep.2019.02.027 | DOI Listing |
Front Vet Sci
December 2024
Intergraduate Degree Program in Integrative and Biomedical Physiology, Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, United States.
Introduction: Clinical metritis (CM) has significant costs to dairy producers. Current treatment strategy involves systemic antibiotics; however, there is increasing concern about judicious antibiotic use. The study objective was to evaluate the effects of a non-antibiotic treatment vs.
View Article and Find Full Text PDFBiochimie
December 2024
Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway.
Skeletal muscle has an important role in whole body energy metabolism and various proteases are involved in skeletal muscle functions. We have previously identified the cysteine protease legumain in cultured human skeletal muscle cells. However, the potential role of legumain in regulation of energy metabolism remains unexplored.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
College of Food Science and Engineering, Shanxi Agricultural University, Taigu 030801, China. Electronic address:
Marinating is a crucial stage in meat processing. However, traditional marinating takes a long time and is prone to nutrient loss. Pulsed electric field (PEF) technology, an innovative non-thermal processing method, has been shown to improve the efficiency of meat marinating.
View Article and Find Full Text PDFJ Environ Manage
December 2024
Chemical and Biochemical Engineering Department, University of Western Ontario, London, ON, N6A 5B9, Canada; Civil and Environmental Engineering Department, University of Western Ontario, London, ON, N6A 5B9, Canada. Electronic address:
The convergence of sustainability and climate change has catalyzed the pursuit of inventive strategies for waste management and sustainable energy production. Hereby, we explored the effect of coupling biochar addition and thermal pretreatment in anaerobic mono-digestion and co-digestion of thermally pretreated thickened waste activated sludge (PTWAS) with food waste (FW). Six semi-continuous lab-scale digesters were operated for 161 days at various organic loading rates (OLR of 2, 3, 4 and 8 kgCOD/m/day) with and without biochar (BC) addition.
View Article and Find Full Text PDFPol J Vet Sci
September 2024
Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-718 Olsztyn, Poland.
This study analysed the influence of montelukast (MON), a cysteinyl leukotriene receptor antagonist, and nifedipine, an L-type voltage-gated Ca2+ channel blocker, on the contractility of the porcine uterine smooth muscle. Myometrial strips were collected from the sexually immature (n=8), cyclic (12-14 days of the oestrous cycle; n=8) and pregnant (27-28 days of pregnancy; n=8) gilts and stimulated with a) MON or nifedipine at concentrations of 10-8-10-4 M and b) increasing concentrations of nifedipine after previous administration of MON at a concentration of 10-4 M. The changes in the tension, amplitude and frequency of contractions were determined with the Hugo Sachs Elektronik equipment for measuring isometric contractions.
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