Commitment Isn't for Everyone.

Trends Parasitol

Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA; Huck Center for Malaria Research, The Pennsylvania State University, University Park, PA, USA; Department of Chemistry, The Pennsylvania State University, University Park, PA, USA. Electronic address:

Published: June 2019

The majority of malaria parasites during human infection are asexual and are unable to be transmitted to mosquitoes. Only sexually differentiated parasites (gametocytes) can be successfully transmitted to complete the lifecycle. In a recent study by Bancells et al. (Nat. Microbiol. 2019;4:144-154), a new route of sexual conversion is identified that does not require a prior round of replication.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163921PMC
http://dx.doi.org/10.1016/j.pt.2019.03.012DOI Listing

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