Getting in LINE with Replication.

Mol Cell

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA; Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA. Electronic address:

Published: May 2019

Sultana et al. (2019) and Flasch et al. (2019) determined integration patterns of human LINE-1 (long interspersed element-1) retrotransposons highlighting their interaction with DNA replication guided by their 5'-TTTT/AA-3' integration motif and nucleotide biases in the genome.

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http://dx.doi.org/10.1016/j.molcel.2019.04.023DOI Listing

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