AI Article Synopsis
- Weng et al. (2019) identify a progenitor population that precedes oligodendrocyte progenitor cells (OPCs) in neural development.
- The study highlights Zfp36l1 as a crucial factor in determining the cell fate between oligodendrocytes and astrocytes among neural progenitors.
- This discovery has implications for understanding processes like myelination and the development of brain tumors (gliomagenesis).
Article Abstract
In this issue of Cell Stem Cell, Weng et al. (2019) characterize a progenitor population that precedes oligodendrocyte progenitor cells (OPCs). The authors identified Zfp36l1 as a key regulator of the cell fate switch between oligodendrocytes and astrocytes in neural progenitors, and thereby an important regulator of cellular processes such as myelination and gliomagenesis.
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| http://dx.doi.org/10.1016/j.stem.2019.04.006 | DOI Listing |
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