A series of phosphinate-containing rhodol and fluorescein dyes are disclosed. These new fluorophores increase the color palette of phosphinate-based xanthenes in the far-red spectral region. The new chemical functionality of these scaffolds is leveraged to produce a sensitive, no-wash imaging probe for cellular esterase activity. The reported phosphinate-containing dyes provide platforms for the further development of imaging probes and self-reporting delivery vehicles.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540752 | PMC |
| http://dx.doi.org/10.1039/c9cc02492a | DOI Listing |
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