Hyperthyroidism during pregnancy is uncommon. Nonetheless, prompt identification and adequate management of hyperthyroidism in a pregnant woman is essential, because uncontrolled thyrotoxicosis significantly increases the risk of maternal and fetal complications. Also, fetal prognosis may be affected by the transplacental passage of maternal thyroid stimulating antibodies or thyrostatic agents, both of which may disrupt fetal thyroid function. Birth defects have been reported in association with the use of antithyroid drugs during early pregnancy. Although rarely, offspring of mothers with Graves' disease may develop fetal/neonatal hyperthyroidism, the management of which requires a close collaboration between endocrinologists, obstetricians, and neonatologists. Because of the above considerations, the management of pregnant and lactating women with hyperthyroidism requires special care, bearing in mind that both maternal thyroid excess and related treatments may adversely affect the newborn's health. In this review we discuss the diagnosis and management of hyperthyroidism in pregnancy, along with the impact of thyrotoxicosis and medications on fetal outcome.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484219 | PMC |
| http://dx.doi.org/10.1016/j.jcte.2019.100190 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Association Between Oral Health Status and Oral Health-Related Quality of Life in Individuals With Thyroid Dysfunction: A Cross-Sectional Study.
Cureus
November 2024
Public Health Dentistry, Government Dental College and Research Institute, Bangalore, IND.
Background and aim Any alterations in the hormonal regulation system such as thyroid dysfunction may have an impact on oral health status, which in turn may affect their oral health-related quality of life (OHRQoL). The objective of this study was to determine the association of thyroid dysfunction on oral health status and OHRQoL of subjects with thyroid dysfunction. Materials and methods A cross-sectional study was conducted among 150 subjects with thyroid dysfunction and 150 subjects without thyroid dysfunction aged 18-60 years from a government hospital in Bangalore city.
View Article and Find Full Text PDFThe relationship between excessive iodine during pregnancy and adverse pregnancy complications.
Endocrine
December 2024
Department of Endocrinology and Metabolism, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Purpose: Iodine nutrition during pregnancy plays an important role in fetal development and maternal outcomes. Iodine deficiency has been proved to be associated with maternal thyroid dysfunction, adverse fetal outcomes and neurodevelopmental disorders in offspring. At present, there are few studies concentrate on the effects of iodine excess during pregnancy on thyroid function, maternal and neonatal outcomes, and the results are still controversial.
View Article and Find Full Text PDFImpact of maternal thyroid dysfunction on fetal and maternal outcomes in pregnancy: a prospective cohort study.
Clin Diabetes Endocrinol
December 2024
Department of Community Medicine, Shri M P Shah Government Medical College, New College Building, GG Hospital Campus, Patel Colony Post, Jamnagar, Gujarat, 361008, India.
Background: Thyroid dysfunction in pregnancy can adversely impact maternal and fetal outcomes. However, the association between thyroid status and specific adverse outcomes needs clarity, especially in understudied regions.
Objective: This prospective cohort study aimed to illuminate the multifaceted associations between maternal thyroid dysfunction and feto-maternal outcomes in Gujarat, India.
A comparative study on the clinical efficacy and pregnancy outcomes of methimazole and propylthiouracil in managing pregnancy complicated with hyperthyroidism.
Afr J Reprod Health
October 2024
Gynecology and obstetrics, Taizhou Women and Children's Hospital of Wenzhou Medical University, TaiZhou, 318000, China.
The objective of the study was to compare the clinical efficacy and pregnancy outcomes of methimazole and propylthiouracil in managing hyperthyroidism during pregnancy. This retrospective analysis included 100 pregnant women with hyperthyroidism, who were divided into two groups: the methimazole group (Group A) and the propylthiouracil group (Group B). Indicators such as thyroid function, liver function, pregnancy outcomes, and newborn health were closely monitored.
View Article and Find Full Text PDFAn unusual case of severe hyperbilirubinemia and thyrotoxicosis.
Endocr Regul
January 2024
Department of General Medicine, Baroda Medical College and SSG Hospital, Vadodara, India.
Article Synopsis
- - A 23-year-old pregnant woman experienced severe jaundice, anemia, dyspnea, and hyperthyroidism after five months of not menstruating.
- - Initial treatments for jaundice were ineffective, leading to a focus on managing her thyroid storm, a serious condition related to hyperthyroidism.
- - The patient's liver dysfunction improved significantly with the use of iodine and thionamides, highlighting a rare link between severe jaundice and thyroid storm during pregnancy.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!