Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689267 | PMC |
| http://dx.doi.org/10.1126/science.aax3221 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Perineuronal Nets in the CNS: Architects of Memory and Potential Therapeutic Target in Neuropsychiatric Disorders.
Int J Mol Sci
March 2024
National Institute on Drug Dependence, Peking University, Beijing 100191, China.
The extracellular matrix (ECM) within the brain possesses a distinctive composition and functionality, influencing a spectrum of physiological and pathological states. Among its constituents, perineuronal nets (PNNs) are unique ECM structures that wrap around the cell body of many neurons and extend along their dendrites within the central nervous system (CNS). PNNs are pivotal regulators of plasticity in CNS, both during development and adulthood stages.
View Article and Find Full Text PDFA spatially-resolved transcriptional atlas of the murine dorsal pons at single-cell resolution.
Nat Commun
March 2024
Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
The "dorsal pons", or "dorsal pontine tegmentum" (dPnTg), is part of the brainstem. It is a complex, densely packed region whose nuclei are involved in regulating many vital functions. Notable among them are the parabrachial nucleus, the Kölliker Fuse, the Barrington nucleus, the locus coeruleus, and the dorsal, laterodorsal, and ventral tegmental nuclei.
View Article and Find Full Text PDFA spatially-resolved transcriptional atlas of the murine dorsal pons at single-cell resolution.
bioRxiv
November 2023
Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
The "dorsal pons", or "dorsal pontine tegmentum" (dPnTg), is part of the brainstem. It is a complex, densely packed region whose nuclei are involved in regulating many vital functions. Notable among them are the parabrachial nucleus, the Kölliker Fuse, the Barrington nucleus, the locus coeruleus, and the dorsal, laterodorsal, and ventral tegmental nuclei.
View Article and Find Full Text PDFAstrocytes and microglia in the coordination of CNS development and homeostasis.
J Neurochem
October 2024
Center for Brain Immunology and Glia, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Glia have emerged as important architects of central nervous system (CNS) development and maintenance. While traditionally glial contributions to CNS development and maintenance have been studied independently, there is growing evidence that either suggests or documents that glia may act in coordinated manners to effect developmental patterning and homeostatic functions in the CNS. In this review, we focus on astrocytes, the most abundant glia in the CNS, and microglia, the earliest glia to colonize the CNS highlighting research that documents either suggestive or established coordinated actions by these glial cells in various CNS processes including cell and/or debris clearance, neuronal survival and morphogenesis, synaptic maturation, and circuit function, angio-/vasculogenesis, myelination, and neurotransmission.
View Article and Find Full Text PDFNanoscale architect: Illuminating the key organizer of the fruit fly's sensory world.
J Cell Biol
October 2023
Department of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Mechanosensory neurons utilize specialized compartments called mechanosensory organelles (MOs) to process external forces, yet the MO organization mechanisms remained unclear. In this issue, Song et al. (2023.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!