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Dosing and Misuse of Buprenorphine in the New Jersey Department of Corrections.
J Am Acad Psychiatry Law
December 2024
Dr. Tamburello is Associate Director of Psychiatry, University Correctional Health Care, and Clinical Professor of Psychiatry, Department of Psychiatry, Rutgers-Robert Wood Johnson Medical School, Piscataway, NJ, USA. Dr. Martin is a staff psychiatrist, VA Pittsburgh Healthcare System, Washington, D.C., USA.
Opioid use disorder is common in incarcerated persons, and concern about the diversion of buprenorphine is a barrier to treatment. We conducted a retrospective chart review of incarcerated persons in the New Jersey Department of Corrections who received charges for misuse of medication, including buprenorphine, hypothesizing that the prescription of buprenorphine monoproduct, multiple tabs or films of buprenorphine, or higher doses of buprenorphine would be associated with more diversion incidents. Within the dosing range of 2 to 12 mg, there were more incidents of diversion of buprenorphine monoproduct (24.
View Article and Find Full Text PDFDirect analysis in real time mass spectrometry (DART-MS/MS) for rapid urine opioid detection in a clinical setting.
Clin Chim Acta
January 2025
Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA. Electronic address:
Background And Aims: Current laboratory methods for opioid detection involve an initial screening with immunoassays which offers efficient but non-specific results and a subsequent liquid chromatography-tandem mass spectrometry (LC-MS/MS) confirmation which offers accurate results but requires extensive sample preparation and turnaround time. Direct Analysis in Real Time (DART) tandem mass spectrometry is evaluated as an alternative approach for accurate opioid detection with efficient sample preparation and turnaround time.
Materials And Methods: DART-MS/MS was optimized by testing the method with varying temperatures, operation modes, extraction methods, hydrolysis times, and vortex times.
Reprint of: Impact of outpatient pharmacist dispensing in an opioid use disorder clinic.
J Am Pharm Assoc (2003)
October 2024
Background: Medications for opioid use disorder are effective in reducing opioid deaths, but access can be an issue. Relocating an outpatient pharmacist for weekly buprenorphine dispensing in an outpatient clinic may facilitate coverage for buprenorphine and mitigate access and counseling barriers.
Objectives: This study aimed to evaluate whether staffing an outpatient resident pharmacist to dispense in the buprenorphine clinic had a positive impact on (1) mean cost per prescription charged to charity care and (2) basic elements of patient satisfaction with the on-site pharmacist.
Impact of outpatient pharmacist dispensing in an opioid use disorder clinic.
J Am Pharm Assoc (2003)
September 2024
Background: Medications for opioid use disorder are effective in reducing opioid deaths, but access can be an issue. Relocating an outpatient pharmacist for weekly buprenorphine dispensing in an outpatient clinic may facilitate coverage for buprenorphine and mitigate access and counseling barriers.
Objectives: This study aimed to evaluate whether staffing an outpatient resident pharmacist to dispense in the buprenorphine clinic had a positive impact on (1) mean cost per prescription charged to charity care and (2) basic elements of patient satisfaction with the on-site pharmacist.
Financial Sustainability of Novel Delivery Models in Behavioral Health Treatment.
J Ment Health Policy Econ
December 2023
Heller School for Social Policy and Management, Brandeis University, Waltham, Massachusetts 02453, United States.
Background: In the US, much of the research into new intervention and delivery models for behavioral health care is funded by research institutes and foundations, typically through grants to develop and test the new interventions. The original grant funding is typically time-limited. This implies that eventually communities, clinicians, and others must find resources to replace the grant funding -otherwise the innovation will not be adopted.
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