The paper describes a multimode-interference-effect-based single-mode-multimode-single-mode (SMS) fiber optic sensing system for wide-range displacement monitoring on an Ilizarov orthopedic external fixation device. Displacement measurement is implemented as the uniform extension of a spring, which is connected to an SMS optical fiber displacement sensor, allowing full displacement characterization. SMS fiber structures are used together with a macrobending-fiber-based interrogation system to measure temperature perturbation and hence eliminate its effect on the displacement measurement. Transmission spectra are measured, achieving a displacement measurement range of 110 mm with maximum sensitivity of -53 pm/mm and a resolution of 500 μm. The all-fiber sensing system has facilitated a clinical device with a wide displacement range operating in real-time when attached to the Ilizarov apparatus.
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http://dx.doi.org/10.1364/AO.58.003209 | DOI Listing |
EMBO J
January 2025
Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, 84112-5650, USA.
Na-K-Cl cotransporters functions as an anion importers, regulating trans-epithelial chloride secretion, cell volume, and renal salt reabsorption. Loop diuretics, including furosemide, bumetanide, and torsemide, antagonize both NKCC1 and NKCC2, and are first-line medicines for the treatment of edema and hypertension. NKCC1 activation by the molecular crowding sensing WNK kinases is critical if cells are to combat shrinkage during hypertonic stress; however, how phosphorylation accelerates NKCC1 ion transport remains unclear.
View Article and Find Full Text PDFInforming and engaging all actors in the land sector, including land-owners and managers, researchers, policy-makers and citizens, on the most effective sustainable land-based solutions and behavioural changes is a key strategy for achieving climate change adaptation and mitigation targets at the global as well as at EU and local level. One requisite to support actors in the land sector is to provide them publicly available, reliable and ready-to-use information related to the implementation of Land-based Adaptation and Mitigation Solutions (LAMS). Here we introduce a LAMS catalogue, a collection of meaningful quantitative and qualitative information on 60 solutions characterised according to a set of specifications (e.
View Article and Find Full Text PDFACS Sens
January 2025
Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin 300384, PR China.
The simultaneous detection of electroencephalography (EEG) signals and neurotransmitter levels plays an important role as biomarkers for the assessment and monitoring of emotions and cognition. This paper describes the development of boron and nitrogen codoped graphene-diamond (BNGrD) microelectrodes with a diameter of only 200 μm for sensing EEG signals and dopamine (DA) levels, which have been developed for the first time. The optimized BNGrD microelectrode responded sensitively to both EEG and DA signals, with a signal-to-noise ratio of 9 dB for spontaneous EEG signals and a limit of detection as low as 124 nM for DA.
View Article and Find Full Text PDFNeurosci Biobehav Rev
January 2025
Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Viale delle Scienze 11, 43125 Parma, Italy.
Perinatal asphyxia (PA) is a leading cause of neonatal morbidity and mortality, often resulting in long-term neurodevelopmental challenges. Despite advancements in perinatal care, predicting long-term outcomes remains difficult. Early diagnosis is essential for timely interventions to reduce brain injury, with tools such as Magnetic Resonance Imaging, brain ultrasound, and emerging biomarkers playing a possible key role.
View Article and Find Full Text PDFTalanta
January 2025
College of Chemistry and Pharmaceutical Engineering, Huanghuai University, Zhumadian 463000, PR China. Electronic address:
FeO nanoparticles (NPs) have emerged as pioneering nanozymes with applications in clinical diagnosis, environmental protection and biosensing. However, it is currently limited by insufficient catalytic activity due to poor electron transfer. In this study, we synthesized electron-rich-Zr-doped defect-rich FeO NPs (ZrFeO) using a one-pot solvothermal method.
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