AI Article Synopsis

  • - The KIR2DL4*037 allele is a variant of the KIR2DL4 gene, which plays a role in the immune system.
  • - It differs from a similar allele, KIR2DL4*00501, by just one missense mutation, meaning one amino acid in the protein sequence has changed.
  • - This single mutation can potentially impact how the immune system functions or interacts with diseases.

Article Abstract

The novel KIR2DL4*037 allele differs from the closest allele KIR2DL4*00501 by a single missense mutation.

Download full-text PDF

Source
http://dx.doi.org/10.1111/tan.13563DOI Listing

Publication Analysis

Top Keywords

novel kir2dl4*037
8
kir2dl4*037 allele
8
characterization novel
4
allele identified
4
identified chinese
4
chinese hani
4
hani individual
4
individual novel
4
allele differs
4
differs closest
4

Similar Publications

Nanoscale Metal-Organic Frameworks for the Co-Delivery of Cycloxaprid and Pooled siRNAs to Enhance Control Efficacy in .

J Agric Food Chem

January 2025

China-Kenya Joint Laboratory for Ecological Pest Control of Citrus, State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Key Laboratory of Biopesticide and Chemical Biology, MOE, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou 350002, China.

RNA pesticides have emerged as a promising alternative to conventional chemical pesticides due to their high specificity and minimal environmental impact. However, the instability of RNA molecules in the environment and the challenges associated with their effective delivery to target pests limit their broader application. This study addresses these challenges by developing a dual delivery system using chitosan (CS) and Metal-Organic Frameworks (MOFs) to enhance the delivery and efficacy of double-stranded RNA (dsRNA) and cycloxaprid against , a vector of citrus greening disease.

View Article and Find Full Text PDF

A tetragonal NaVPOF coated with reduced graphene oxide (rGO) manifests an outstanding high-rate capability of 90.6 mA h g at 10C and a stable capacity of 41.9 mA h g after 4000 cycles at 30C owing to the enhanced electronic conductivity and improved Zn diffusion capability from the rGO coating.

View Article and Find Full Text PDF

Efforts to effect racial health disparity (RHD) policy change are urgent, necessary, and subject to a key barrier: defensiveness among White privileged audiences. Within the literature to date, such defensiveness is under-investigated, and when examined, is typically conceived of as an individual cognitive outcome-a message effect-rather than a communication interaction. Yet policy change advocacy efforts, ranging from community organizing to change campaigns, necessitate communication interactions between advocates and privileged policy change audiences, such as neighborhood groups or policymakers themselves.

View Article and Find Full Text PDF

Microfluidic-based redesign of a humidity-driven energy harvester.

Lab Chip

January 2025

Human Augmentation Research Center, National Institute of Advanced Industrial Science and Technology, 6-2-3, Kashiwanoha, Kashiwa, Chiba 277-0882, Japan.

Integrating microfluidic elements onto a single chip offers many advantages, including miniaturization, portability, and multifunctionality, making such systems highly useful for biomedical, healthcare, and sensing applications. However, these chips need redesigning for compatibility with microfluidic fabrication methods such as photolithography. To address this, we integrated microfluidics technology into our previously developed humidity-driven energy harvester to create a self-powered system and redesigned it so that it could be fabricated using photolithography and printing.

View Article and Find Full Text PDF

Recent Advancements in Drug Targeting for Ferroptosis as an Antitumor Therapy: Development of Novel therapeutics.

Curr Cancer Drug Targets

January 2025

Department of Chemistry, Siddhachalam Laboratory, Raipur, 493221, Chhattisgarh, India.

Objectives: The primary objective of this review is to provide updated mechanisms that regulate ferroptosis sensitivity in cancer cells and recent advancements in drug targeting for ferroptosis as an antitumor therapy.

Methods: To achieve these objectives, a comprehensive literature review was conducted, analyzing recent studies on ferroptosis, including its cellular, molecular, and gene-level characteristics. The review involved an evaluation of advancements in ferroptosis drug research across various medical domains, with particular attention to novel therapeutic approaches in nano-medicine, TCM, and Western medicine.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!