Compliant Parallel Mechanisms (CPMs) are widely used in micro/nano-positioning systems. In recent years, CPMs with a large travel range (≥1 mm) have been getting increasing attention. In this paper, a 3 Prismatic-Prismatic-Revolute (3PPR) planar CPM with a motion range of 5 mm × 5 mm × 5° is designed. The mechanical structure is characterized by the application of three joints based on a compliant four-bar mechanism, which guarantees the motions along/about the specific axes to improve motion accuracy. A double blade rotary pivot is served as a revolute joint to decrease the drift of pivot and produce a large rotation range without loss of compactness. The compliance matrix method is implemented to kinetostatic modeling, and the input coupling effect, which is always neglected or modeled complicatedly in 3-Degree-of-Freedom planar CPMs, is involved with the principle of superposition. The feasibility of the mechanical design and the accuracy of the developed kinetostatic model are validated by finite element analysis and experiments, respectively. The results indicate that the modeling method based on the compliance matrix method is concise, effective, and accurate, and can be extended to other more complicated CPMs.
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http://dx.doi.org/10.1063/1.5080252 | DOI Listing |
Cureus
December 2024
General Surgery, Father Muller Medical College, Mangalore, IND.
Background Wound healing in diabetic foot ulcers (DFUs) is hindered by several physiological and biochemical abnormalities, including prolonged inflammation, an imbalance in extracellular matrix (ECM) synthesis and degradation, insufficient neovascularization, and reduced macrophage activity. In DFUs, excessive and uncontrolled matrix metalloproteinases (MMPs) degrade the ECM and impede wound healing. Matrix metalloproteinase-9 (MMP-9) concentration plays a key role in inflammation and ECM degradation.
View Article and Find Full Text PDFCureus
December 2024
Department of Pathology, General Hospital of Thessaloniki Agios Pavlos, Thessaloniki, GRC.
The term "gossypiboma" or "textiloma" is used to describe a mass of retained cotton matrix and the surrounding inflammatory response inside a body cavity following surgical intervention. The precise incidence of this phenomenon is uncertain, as cases are frequently underreported due to concerns related to medical malpractice. This rare complication poses a diagnostic dilemma due to the non-specific clinical and radiological features, which can result in significant morbidity and mortality.
View Article and Find Full Text PDFHemostasis is a critical aspect of holmium laser enucleation of the prostate (HoLEP) for benign prostatic hyperplasia (BPH). While HoLEP offers superior outcomes compared to traditional techniques, effective intraoperative and postoperative bleeding control remains a challenge. This report evaluates the feasibility and safety of PuraBond® (3-D Matrix, Ltd.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
Laboratoire d'Energétique et des Transferts Thermique et Massique (LETTM), Faculté des Sciences de Tunis, Université de Tunis El Manar, Campus Universitaire El-Manar, El Manar, Tunis 2092, Tunisia.
The viability of using fibers as reinforcement material for developing lightweight sustainable non-structural construction materials in compliance with the valorization of local by-products has been investigated in this work. This study aims to investigate the effect of the chemical treatment of fibers on the mechanical and hygric properties of bio-sourced clay-sand- fiber composite. This lightweight specimen has been produced from a mixture of 60% natural clay and 40% sand by mass, as a matrix, and reinforced with different amounts of Juncus fibers.
View Article and Find Full Text PDFJ Cancer Policy
January 2025
Institute of Health, Jimma University, Jimma, Ethiopia.
Cervical cancer is the second most prevalent disease among Ethiopian women of reproductive age and a serious gynecological malignancy affecting women regionally. About, 3,235 deaths and 4,648 new cases are reported nationwide each year. Precancerous cervical screening programs face many difficulties in settings with limited resources, despite their severity, such as a lack of medical supplies and equipment, poorly trained healthcare workers, a heavy workload for current staff, low professional compliance, and insufficient support from medical facilities.
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