Aim Of The Study: To assess public knowledge, attitude, and believes toward the epilepsy among local community populations in Shaqra Area, Kingdom of Saudi Arabia.
Methods: An organized 14 questionnaire was prepared to analyze public knowledge attitudes and believes about epilepsy. Study was conducted randomly in common public places in Shaqra City, Saudi Arabia, during the months of April and May 2016. Sample size includes 155 males and 130 females from Shaqra City of Saudi Arabia.
Results: The study analyzed the 285 local public including 155 male and 130 female contributors. About 68.38% male contributors and 63.07% female contributors studied Diploma or Bachelor education program. Female contributors (71.53%) were aware about epilepsy as compared with male contributors (58.70%). Maximum number of female contributors (82.30%) believes that epilepsy is treated by medication as compared with male contributors (58.70%).
Conclusion: The knowledge, awareness, and attitudes of the epilepsy are found to be much improved in local community of Saudi Arabia. In the modern era, people assume that epilepsy is still due to evil spirit. Many contributors think there should be restrictions on driving and getting jobs in epilepsy patient. Public awareness and educational campaigns should be included in modern methods of education to develop well-knowledged community, which will improve the quality of life of epileptic patients.
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http://dx.doi.org/10.4103/jfmpc.jfmpc_425_18 | DOI Listing |
F1000Res
January 2025
Faculty of Teaching and Education Sciences, Islamic University of Malang, Malang, East Java, Indonesia.
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Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, Shandong, China.
-Methyl-d-aspartate (NMDA) receptors, a subtype of ionotropic glutamate receptors in the central nervous system (CNS), have garnered attention for their role in brain disorders. Specifically, GluN2A-containing NMDA receptors have emerged as a potential therapeutic target for the treatment of depressive disorders and epilepsy. However, the development of GluN2A-containing NMDA receptor-selective antagonists, represented by -(4-(2-benzoylhydrazine-1-carbonyl)benzyl)-3-chloro-4-fluorobenzenesulfonamide (TCN-201) and its derivatives, faces a significant challenge due to their limited ability to penetrate the blood-brain barrier (BBB), hampering their characterization and further advancement.
View Article and Find Full Text PDFChaos
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Departamento de Física, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Santa Catarina, Brazil.
The presence of chaos is ubiquitous in mathematical models of neuroscience. In experimental neural systems, chaos was convincingly demonstrated in membranes, neurons, and small networks. However, its effects on the brain have long been debated.
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SynGAP Research Fund, 2856 Curie Pl., San Diego, CA 92122, USA.
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View Article and Find Full Text PDFPharm Res
January 2025
Penn State Cancer Institute, Pennsylvania State University, Hershey, PA, 17033, USA.
Angelica gigas Nakai (AGN) root is a medicinal herbal widely used in traditional medicine in Korea. AGN root ethanolic extracts have been marketed as dietary supplements in the United States for memory health and pain management. We have recently reviewed the pharmacokinetics (PK) and first-pass hepatic metabolism of ingested AGN supplements in humans for the signature pyranocoumarins decursin (D, C 1x), decursinol angelate (DA, C ~ 10x) and their common botanical precursor and hepatic metabolite decursinol (DOH, C ~ 1000x).
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