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Smartphone-Assisted EY@MOF-5-Based Dual-Emission Fluorescent Sensor for Rapid On-Site Detection of Daclatasvir and Nitenpyram.
ACS Appl Mater Interfaces
January 2024
HEJ Research Institute of Chemistry, International Center for Chemical and Biological Science (ICCBS), University of Karachi, Karachi 75270 Pakistan.
Fluorescent metal-organic frameworks (MOFs) are promising sensing materials with tunable and robust structural properties and remarkable luminescent capabilities. In this study, a novel dual-emission fluorescent metal-organic framework (EY@MOF-5) composite is synthesized by a one-pot bottle-around-ship approach. Eosin Y (EY) is encapsulated in MOF-5 to enhance its fluorescence properties and selectivity, effectively addressing typical MOF-5 limitations.
View Article and Find Full Text PDFA community-based strategy to eliminate hepatitis C among people who inject drugs in Vietnam.
Lancet Reg Health West Pac
August 2023
Pathogenesis and Control of Chronic and Emerging Infections, Université de Montpellier, Inserm, Etablissement Français du Sang, Montpellier, France.
Background: Towards hepatitis C elimination among people who inject drugs (PWID), we assessed the effectiveness of a strategy consisting of a community-based respondent-driven sampling (RDS) as wide screening, a simplified and integrated hospital-based care, and prevention of reinfection supported by community-based organisations (CBO), in Hai Phong, Vietnam.
Methods: Adults who injected heroin were enrolled in a RDS survey implemented in two CBO premises. Rapid HIV and HCV tests were done on site, and blood was taken for HCV RNA testing.
Hepatitis C treatment program in Maputo, Mozambique, the challenge of genotypes and key populations: A 5-year retrospective analysis of routine programmatic data.
Health Sci Rep
April 2023
Médecins Sans Frontières (MSF) Maputo Mozambique.
Background And Aims: Hepatitis C (HCV) programs face challenges, especially linked to key populations to achieve World Health Organization (WHO) goals of eliminating hepatitis. Médecins Sans Frontières and Mozambique's Ministry of Health first implemented HCV treatment in Maputo, in 2016 and harm reduction activities in 2017.
Methods: We retrospectively analyzed routine data of patients enrolled between December 2016 and July 2021.
Epidemiological characteristics and real-world treatment outcomes of hepatitis C among HIV/HCV co-infected patients in Myanmar: A prospective cohort study.
Health Sci Rep
February 2023
Epicentre, Medecins Sans Frontieres Paris France.
Background And Aims: In Myanmar, public sector treatment programs for hepatitis C virus (HCV) infection were nonexistent until June 2017. WHO highlights the importance of simplification of HCV service delivery through task-shifting among health workers and decentralization to the primary health care level. Between November 2016 and November 2017, a study was conducted to describe the epidemiological data and real-world outcomes of treating HIV/HCV coinfected patients with generic direct acting antiviral (DAA) based regimens in the three HIV clinics run by nonspecialist medical doctors in Myanmar.
View Article and Find Full Text PDFIdentification of host transcriptome-guided repurposable drugs for SARS-CoV-1 infections and their validation with SARS-CoV-2 infections by using the integrated bioinformatics approaches.
PLoS One
April 2022
Bioinformatics Lab., Department of Statistics, Rajshahi University, Rajshahi, Bangladesh.
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is one of the most severe global pandemic due to its high pathogenicity and death rate starting from the end of 2019. Though there are some vaccines available against SAER-CoV-2 infections, we are worried about their effectiveness, due to its unstable sequence patterns. Therefore, beside vaccines, globally effective supporting drugs are also required for the treatment against SARS-CoV-2 infection.
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