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The First Patient with Tinea Manuum because of Isolated in Malta.
Skinmed
January 2025
Department of Dermatology, Mater Dei Hospital, Msida, Malta.
A 39-year-old woman presented to the dermatology department in January 2022 with a 3-week history of a progressively enlarging and intensely pruritic erythematous annular nodule on her left hand. The lesion started as a small blister, which was initially presumed to be a flare up of her pompholyx dermatitis. On her physician's advice, she applied clobetasol propionate ointment twice daily for 5 days; however the blister continued to increase in size until it burst, revealing raw inflamed skin.
View Article and Find Full Text PDFSkin barrier dysfunction in cutaneous T-cell lymphoma: From pathogenic mechanism of barrier damage to treatment.
Crit Rev Oncol Hematol
January 2025
Department of Dermatology, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, Sichuan 610041, China. Electronic address:
Cutaneous T-cell lymphoma (CTCL) is a group of non-Hodgkin lymphomas characterized by multiple erythematous patches, plaques, or even nodules on the skin. As the disease progresses, patients develop widespread pruritic skin lesions, leading to skin barrier dysfunction, which significantly impacts their quality of life, appearance, and social adaptation. The pathogenesis of CTCL is not fully understood.
View Article and Find Full Text PDFWells Syndrome: A Rare Skin Manifestation of Non-Hodgkin's Lymphoma.
Cureus
October 2024
Pathology, Lakeshore Hospital and Research Centre, Ernakulam, IND.
Eosinophilic cellulitis, also known as Wells syndrome, presents a wide range of morphological spectrum, from pruritic erythematous papules, nodules, and pustules to urticarial and bullous lesions. This is a rare dermatological condition and is known to develop after treatment of hematological malignancy. Here, we report a case of Wells syndrome that was the initial presentation of lymphoma, preceding all other symptoms by six months.
View Article and Find Full Text PDFDupilumab combined with corticosteroid therapy for Kimura disease with multiple systemic masses: a case report and literature review.
Front Immunol
November 2024
Department of Dermatology, Shenzhen University General Hospital, Shenzhen, Shenzhen, China.
Article Synopsis
- Kimura's disease (KD) is a rare condition with unclear causes, no standardized diagnostic criteria, and varied clinical presentations, leading to ongoing research for optimal treatment strategies.
- The paper discusses a case of a 37-year-old Chinese woman who experienced 12 years of skin issues and limb swelling before being diagnosed with KD, resulting in a specific treatment plan combining dupilumab and oral corticosteroids.
- After treatment, the patient had significant improvements with reduced nodules and lower levels of serum IgE, eosinophils, and basophils, indicating the effectiveness of the combined therapy for KD and concurrent atopic dermatitis.
A case of indeterminate cell histiocytosis with ETV3-NCOA2 translocation.
J Dermatol
November 2024
Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Indeterminate cell histiocytosis (ICH) is a rare histiocytic disorder characterized by a proliferation of CD1a and CD207/langerin cells. Recent molecular analyses have identified ETV3-NCOA2 translocation as a possible aetiopathogenesis of ICH. Herein, we describe the first Japanese case of ICH with ETV3-NCOA2 translocation.
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