A callosal projection of area 17 upon the dorsomedial visual area in the marmoset monkey was demonstrated by means of retrograde transport of neuronal tracers. The projection was restricted to those regions representing the vertical meridian in the two areas. This finding, and the data of other authors, indicate that the monkey area 17 projects transcallosally onto homotopic and several heterotopic targets.
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http://dx.doi.org/10.1016/0006-8993(87)90137-5 | DOI Listing |
JAMA Netw Open
December 2024
Departments of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai, New York City, New York.
Importance: Amidst an unprecedented opioid epidemic, identifying neurobiological correlates of change with medication-assisted treatment of heroin use disorder is imperative. White matter impairments in individuals with heroin use disorder (HUD) have been associated with drug craving, a reliable predictor of treatment outcomes; however, little is known about structural connectivity changes with inpatient treatment and abstinence in individuals with HUD.
Objective: To assess white matter microstructure and associations with drug craving changes with inpatient treatment in individuals with HUD (effects of time and rescan compared with controls).
EMBO Mol Med
November 2024
Institut de Génétique et de Biologie Moléculaire et Cellulaire, IGBMC, Illkirch, F-67404, France.
Biochem Biophys Res Commun
November 2024
Department of Biochemistry, Chungbuk National University, Cheongju, 28644, Republic of Korea. Electronic address:
The transcription factor LHX2 contains a LIM domain and plays an important role in the development of the vertebrate nervous system. Although much research has been conducted on the function of Lhx2 during cerebral development, its role in postmitotic neuron differentiation in the cerebral cortex remains unknown. Therefore, this study was conducted to determine the function of Lhx2 in dynamic and elaborate developmental processes, including neurogenesis.
View Article and Find Full Text PDFAm J Psychiatry
October 2024
Department of Psychiatry (Arion, Enwright, Gonzalez-Burgos, Lewis) and Department of Neuroscience (Lewis), University of Pittsburgh, Pittsburgh.
Trends Neurosci
September 2024
Laboratory of Molecular Regulation of Neurogenesis, GIGA Institute, University of Liège, Liège 4000, Belgium; WELBIO department, WEL Research Institute, Avenue Pasteur, 6, 1300 Wavre, Belgium. Electronic address:
The maturation of cerebral cortical networks during early life involves a major reorganization of long-range axonal connections. In a recent study, Bragg-Gonzalo, Aguilera, et al. discovered that in mice, the interhemispheric connections sent by S1L4 callosal projection neurons are pruned via the tight control of their ipsilateral synaptic integration, which relies on the early activity of specific interneurons.
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