A fluorinated aza-BODIPY derivative for NIR fluorescence/PA/F MR tri-modality in vivo imaging.

Lianhua Liu Yaping Yuan Yuqi Yang Michael T McMahon Shizhen Chen Xin Zhou

Chem Commun (Camb)

State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan National Laboratory for Optoelectronics, Wuhan 430071, China.

Published: May 2019

A new fluorinated aza-BODIPY compound, named BDPF, was created to serve as a contrast agent for imaging.
It demonstrated effective imaging capabilities in three modalities: near-infrared fluorescence, photoacoustic imaging, and fluorine-19 magnetic resonance (MR) imaging.
This tri-modal approach provides a comprehensive tool for tumor imaging, enhancing diagnostic accuracy.

A fluorinated aza-BODIPY derivative BDPF was developed as a small molecule contrast agent, which displayed highly efficient near infrared fluorescence/photoacoustic/19F MR tri-modality tumor imaging.

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http://dx.doi.org/10.1039/c9cc01253b	DOI Listing

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