Amygdaloid cysts are benign dysembryologic cystic tumors developing in the anterolateral portion of the neck. They account for 2% of all neck tumors located in the laterocervical region. They mostly result from branchial cleft abnormalities, accounting for 6.1-85.2% of all second branchial cleft abnormalities. They are due to the persistence of the cervical sinus during the differentiation of the branchial apparatus. They manifest as a laterocervical swelling in the anterior edge of the sternocleidomastoid muscle. The diagnosis of cyst is confirmed by ultrasound and CT scan. Treatment is based on surgical resection. We here report the case of a 24-year old woman presenting with voluminous left laterocervical swelling evolving over the past 3 years without any associated symptoms. Exploratory cervicotomy with anatomopathological examination were performed. The histologic diagnosis of amygdaloid cyst with no sign of malignancy was retained. This study aims to analyze the anatomoclinical features and to discuss the therapeutic options for the management of this disease.
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http://dx.doi.org/10.11604/pamj.2018.31.147.17028 | DOI Listing |
Front Pediatr
December 2024
Department of Ultrasound, Jinan Maternity and Child Care Hospital, Jinan, Shandong, China.
Congenital melanocytic nevus (CMN) syndrome is a rare, non-familial neural ectodermal dysplasia characterized by CMN combined with extracutaneous abnormalities, predominantly involving the central nervous system (CNS). The pathogenesis of CMN syndrome is thought to result from early post-zygotic somatic mutations. CNS melanosis frequently affects the anterior temporal lobes, brainstem, cerebellum, and cerebral cortex.
View Article and Find Full Text PDFIBRO Neurosci Rep
December 2023
Department of Physiology, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, SP, Brazil.
About 1-2% of people worldwide suffer from epilepsy, which is characterized by unpredictable and intermittent seizure occurrence. Despite the fact that the exact origin of temporal lobe epilepsy is frequently unknown, it is frequently linked to an early triggering insult like brain damage, tumors, or (SE). We used an experimental approach consisting of electrical stimulation of the amygdaloid complex to induce two behaviorally and structurally distinct SE states: Type I (fully convulsive), with more severe seizure behaviors and more extensive brain damage, and Type II (partial convulsive), with less severe seizure behaviors and brain damage.
View Article and Find Full Text PDFCureus
November 2022
Department of Otolaryngology, Head and Neck Surgery, University Hospital Center Mohammed VI, Mohammed First University, Faculty of Medicine and Pharmacy, Oujda, MAR.
Amygdaloid cysts are benign dysembryological cystic tumors that develop in the antero-lateral part of the neck; they represent 2% of laterocervical tumors of the neck; they are among the most frequent gill anomalies; they represent 6.1% to 85.2% of second cleft anomalies.
View Article and Find Full Text PDFPharmacol Rep
February 2022
Department of Clinical Pharmacology, Faculty of Medicine, School of Health Sciences, Aristotle University of Thessaloniki, 54124, Thessaloníki, Greece.
Background: Circulating cytokines have been proposed to be implicated in the development of mood disorders and cognitive impairment. This study aims to examine the effect of chronic treatment with infliximab, a tumor necrosis factor-alpha (TNF-alpha) inhibitor, and tocilizumab, an antibody against interleukin-6 (IL-6) receptor on anxiety-like behavior and cognitive function.
Methods: Twenty-eight male, Wistar rats were randomly allocated into negative control, vehicle, infliximab and tocilizumab groups.
Int Immunopharmacol
October 2021
Department of Clinical Pharmacology, School of Medicine, Aristotle University of Thessaloniki, University Campus 54124 Thessaloniki, Greece.
Several studies have demonstrated that rheumatic diseases, including Juvenile Idiopathic Arthritis (JIA), are associated with anxiety-like behavior and a cognitive decline. Infliximab, a Tumor Necrosis Factor-alpha (TNF-a) inhibitor, and tocilizumab, an antibody against Interleukin-6 (IL-6) receptor, are commonly used in the treatment of JIA. Here, we aimed to evaluate the effects of infliximab and tocilizumab on anxiety symptoms and cognitive function in a juvenile model of severe autoimmune arthritis.
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