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A Quality Improvement Initiative to Reduce Surgical Site Infections in Pediatric Patients Undergoing Cardiothoracic Surgery.
Pediatr Qual Saf
January 2025
Division of Cardiology, Department of Pediatrics, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Ga.
Article Synopsis
- The project focused on reducing surgical site infections (SSIs) in pediatric patients undergoing cardiothoracic surgery to less than 1 per 100 cases.
- A multidisciplinary team identified risk factors and created a quality improvement (QI) initiative, which included enhanced hygiene practices and wound care education.
- The result was a significant decrease in SSIs, dropping from 2.82 to 0.55 per 100 cases, without any increase in major complications or mortality.
Cleft palate, congenital heart disease, and developmental delay involving heterozygous mutations found in the patient with attention deficit hyperactivity disorder: a case report.
Front Pediatr
December 2024
Key Laboratory of Birth Defects and Related Diseases of Women and Children of Ministry of Education (MOE), Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
This case is the first reported patient with a gene mutation who primarily exhibits pronounced inattention as the main manifestation and is diagnosed with ADHD, requiring methylphenidate treatment. It is characterized by unique clinical features that set it apart from previously reported cases with mutations in the gene. Here, we report a female child with a diagnosis of ADHD and comorbidities.
View Article and Find Full Text PDFThe risk factors and prediction model for postoperative pneumonia after craniotomy.
Front Cell Infect Microbiol
December 2024
Nursing Department, Chengfei Hospital, Chengdu, China.
Background: Craniotomy is highly susceptible to postoperative pneumonia, which significantly impacts the outcomes of patients undergoing such procedures. Our study aims to examine the risk factors associated with postoperative pneumonia and establish a predictive model with a nomogram to assess this risk.
Methods: We conducted a matched 1:1 case-control study involving 831 adult patients undergoing craniotomy at our hospital.
Evaluation of circ_0002232 and circ-vimentin gene expressions as valuable biomarkers in acute myeloid leukemia patients.
Mol Biol Rep
January 2025
Department of Clinical Pathology, South Egypt Cancer Institute, Assiut University, Assiut, Egypt.
Background And Aim: Acute myeloid leukemia (AML) is a remarkably complex malignancy; with considerable genetic, epigenetic, and phenotypic heterogenicity. Circ-RNAs are a novel class of non-coding RNA. They may influence leukemia development and offer exciting possibilities for targeted AML diagnosis and therapy.
View Article and Find Full Text PDFA retrospective analysis of cardiovascular outcomes of clozapine treated individuals within Hunter New England.
Intern Med J
January 2025
Cardiology Department, John Hunter Hospital Newcastle, Newcastle, New South Wales, Australia.
Background: Clozapine has demonstrated superiority in improving both positive and negative symptoms of treatment-resistant schizophrenia; however, there are associated treatment-limiting side effects, including myocarditis, cardiomyopathy and agranulocytosis.
Aim: This retrospective cohort study describes the prevalence of myocarditis, left ventricular (LV) dysfunction, cardiovascular risk factors and outcomes in a cohort of patients maintained on clozapine therapy.
Methods: Data were retrospectively collated from patients who had a diagnosis of schizophrenia, had been managed with clozapine at any stage during their care and undergone at least one echocardiogram.
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