Metal-hydride hydrogen atom transfer (MHAT) functionalizes alkenes with predictable branched (Markovnikov) selectivity. The breadth of these transformations has been confined to π-radical traps; no sp electrophiles have been reported. Here we describe a Mn/Ni dual catalytic system that hydroalkylates unactivated olefins with unactivated alkyl halides, yielding aliphatic quaternary carbons.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923049 | PMC |
| http://dx.doi.org/10.1021/jacs.9b02844 | DOI Listing |
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