AI Article Synopsis
- - The study compared two methods of cell-free and concentrated ascites reinfusion therapy (CART): the internal filtration pressure method and the external filtration pressure method, focusing on circuit pressure and component recovery rates.
- - The internal method showed significantly higher recovery rates for immunoglobulins (IgG, IgA, IgM) and haptoglobin compared to the external method, while the recovery of α-antitrypsin was lower in the internal method.
- - Higher levels of certain proteins like IL-6, haptoglobin, and α-antitrypsin were observed in patients where circuit pressure rose, suggesting these proteins could be linked to the increase in circuit pressure during the therapy.
Article Abstract
Cell-free and concentrated ascites reinfusion therapy (CART) by internal filtration pressure method (internal method) and external filtration pressure method (external method) using the same cancerous ascites was performed. The rate of rise in circuit pressure and recovered components were compared between the two methods. The factors related to circuit pressure rise were also researched. In both methods, circuit pressure rose in 50% of cases. The recovery rates of IgG, IgA, IgM, and haptoglobin were significantly higher for the internal method than for the external method, whereas the recovery rate of α -antitrypsin was significantly lower in the internal method than in the external method. The levels of IL-6, haptoglobin, α -antitrypsin, and fibrinogen/fibrindegradation products (FDP) in the original ascites were significantly higher in the group wherein circuit pressure rose than in that without circuit pressure rise. These proteins might be related to the rise in circuit pressure.
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| http://dx.doi.org/10.1111/1744-9987.12821 | DOI Listing |
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