Design of photosensitizers capable of generating singlet oxygen is crucial for the success of photodynamic therapy, and biocompatible supramolecular systems are emerging in this area. We report a supramolecular nanocomposite consisting of BODIPY, tryptophan and gold nanoparticles. While the individual components in isolation were inactive, the nanocomposite was found to be photostable and exhibited efficient photosensitization properties.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c9cc02480h | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Portable Amperometric Biosensor Enhanced with Enzyme-Ternary Nanocomposites for Prostate Cancer Biomarker Detection.
Biosensors (Basel)
December 2024
Department of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan 46241, Republic of Korea.
Enzyme-based portable amperometric biosensors are precise and low-cost medical devices used for rapid cancer biomarker screening. Sarcosine (Sar) is an ideal biomarker for prostate cancer (PCa). Because human serum and urine contain complex interfering substances that can directly oxidize at the electrode surface, rapid Sar screening biosensors are relatively challenging and have rarely been reported.
View Article and Find Full Text PDFPolymer Films' Residual Stress Attenuation from the Supramolecular Complexation with Ultra-Small Nanoparticles for High Resolution Nanoimprint Lithography.
Angew Chem Int Ed Engl
December 2024
State Key Laboratory of Luminescent Materials and Devices &, South China Advanced Institute for Soft Matter Science and Technology, Guangdong Basic Research Center of Excellence for Energy &, Information Polymer Materials, South China University of Technology, 510640, Guangzhou, P. R. China.
Nanoimprint lithography (NIL) has been broadly applied in the fabrication of nano-patterned polymer films for cost-efficiency and high through-put; however, the intrinsic tradeoff between mechanical strength and residual stress of polymer films significantly limits the NIL resolution while the harsh processing conditions limit its versatile applications to different substrates. Herein, 1 nm metal oxide cluster, phosphotungstic acid (PTA), is used to complex with polyvinyl alcohol (PVA) for high-resolution NIL that can be operated at large-scale and mild conditions. The ultra-small size of PTA enables dense supramolecular interaction with PVA for the diminished crystallinity and accelerated chain dynamics that help relax the residual stress during film casting.
View Article and Find Full Text PDFMolecular structure data and modelling roadmap for optimized oxidized graphene quantum dot and epoxy interface and mechanical properties.
Data Brief
December 2024
San Jose State University, 1 Washington Sq., San Jose, CA 95192, United States.
Article Synopsis
- Hybrid epoxy composites are considered ideal for low-density applications due to their high specific strength and stiffness, enhanced further by adding nanofillers like carbon nanotubes and graphene.
- Graphene quantum dots (GQDs) are particularly effective due to their small size, which improves the interfacial interactions and overall mechanical properties of the composite, overcoming issues commonly associated with traditional fillers.
- This study employs a molecular dynamics workflow to simulate the effects of functionalized GQDs in an epoxy matrix, revealing significant gains in strength (up to 56%) and stiffness (18%) from oxidized GQD-epoxy composites.
Photocurable Sol-Gel Formulations for the Fabrication of Titanium Carbide/Carbon Nanocomposites via Digital Light Processing.
ACS Appl Mater Interfaces
December 2024
Department of Industrial Engineering, University of Padova, Via Marzolo 9, Padova 35131, Italy.
Additive manufacturing of carbide materials has received significant attention in the past years due to the ability to fabricate complex structures over different length scales. However, the typical limitations for powder-laden inks, such as nozzle clogging, rheological and geometric constraints, particle sedimentation, light-scattering and absorbing phenomena, narrow the range of available processes to manufacture carbide materials via conventional particle-based systems. To address these shortcomings, we have developed a one-pot synthetic route for the preparation of sol-gel-based UV-photocurable formulations, aiming at the fabrication of titanium carbide/carbon nanocomposites using digital light processing printing, pointing to potential applications in the field of nuclear physics.
View Article and Find Full Text PDFCorrole-based photothermal nanocomposite hydrogel with nitric oxide release for diabetic wound healing.
Acta Biomater
January 2025
Department of Cardiovascular Surgery, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE), School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China. Electronic address:
The management of chronic diabetic wounds remains a significant challenge due to persistent bacterial infections and impaired angiogenesis. Herein, we reported a nanocomposite hydrogel (M/P-SNO/G) incorporated with M/P-SNO nanoparticles engineered by supramolecular assembly of the photosensitizing mono-carboxyl corrole (MCC) and S-nitrosothiol-modified polyethylene glycol (mPEG-SNO) for synergistic photothermal therapy (PTT)/nitric oxide (NO) treatment of diabetic wounds. The strong π-π interaction among aggregated MCC in M/P-SNO enhances the optical absorption and photothermal ability, thereby facilitating the precise release of NO upon laser irradiation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!