Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
[Detection and Treatment for Hemolytic Transfusion Reaction in Patient with Combined Antibody Consisted of Anti-Fy and Anti-Jk].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
December 2024
Department of Blood Transfusion, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China.
Objective: To investigate and assess hemolytic transfusion reaction in patient with complex and combined anti-Fy and anti-Jk which so as to provide a safety blood transfusion strategy.
Methods: ABO/Rh blood grouping, antibody screening and identification, and Coombs' tests were performed by the routine serological methods include manual tube and automatic blood group analyzer with matching micro-column gel cards from Diagnostic Grifols and Jiangsu LIBO. The hospital information system and laboratory information system were used to collect dada on patients' blood routine tests, liver and kidney function, coagulation, cardiac function, and other clinical indicators before and after blood transfusion were analyzed and compared in conjunction with the patients' clinical manifestations.
Massive transfusion of incompatible red blood cells: A case report demonstrating the benefits of a regional patient alloantibody registry and prompt automated red cell exchange.
Transfusion
December 2024
Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA.
Article Synopsis
- Emergent transfusion can lead to serious complications like hemolysis, especially when red blood cells are incompatible with a patient’s known antibody profile.
- A 77-year-old woman who experienced significant hemorrhage received transfusions without standard testing and was later found to have multiple incompatible antibodies, highlighting the risks.
- Successful treatment of her transfusion-related hemolysis was achieved through automated red cell exchange, demonstrating the importance of having access to an alloantibody registry for timely intervention.
An unusual case of reagent interference in transfusion medicine workup: Pan reactive indirect antiglobulin test caused by commercial saline solution.
Transfus Med
November 2024
Department of Clinical Immunology, Odense University Hospital, Odense, Denmark.
Background: At the regional transfusion service in the Region of Southern Denmark, serological investigations are primarily carried out using column agglutination techniques. This case study examines an unusual instance of reagent interference in pretransfusion testing using column agglutination at the Hospital of Southern Denmark, Aabenraa.
Case Presentation: A 72-year-old male patient presented for pretransfusion testing prior to hernia surgery.
Variations in antenatal management and outcomes in haemolytic disease of the fetus and newborn: an international, retrospective, observational cohort study.
Lancet Haematol
December 2024
Division of Foetal Medicine, Department of Obstetrics, Leiden University Medical Centre, Leiden, Netherlands. Electronic address:
Background: Advances in haemolytic disease of the fetus and newborn have led to numerous treatment options. We report practice variations in the management and outcomes of haemolytic disease of the fetus and newborn in at-risk pregnancies.
Methods: In this international, retrospective, observational cohort study, data from cases with moderate or severe haemolytic disease of the fetus and newborn were retrieved from 31 centres in 22 countries.
Article Synopsis
- - A delayed hemolytic transfusion reaction (DHTR) can occur in sickle cell disease (SCD) patients after receiving blood transfusions, leading to serious anemia weeks later due to immune responses to foreign red blood cell antigens.
- - The case study describes a pediatric SCD patient who experienced DHTR after her second transfusion, emphasizing the importance of extending RBC antigen profiling through molecular genotyping instead of just serology.
- - Molecular genotyping offers better accuracy in matching blood types, which can help prevent complications during transfusions and improve management by quickly identifying rare donors when needed.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!