Memory monitoring is an inferential process that we use to evaluate and make judgments about the contents of our memory. Prior work has shown age-related similarity in prospective monitoring of ongoing memory processes, but age-related deficits when retrospectively monitoring the source of memories. In the current study, we examined how extrinsic and intrinsic cues influence age differences in these 2 forms of memory monitoring. Two experiments were conducted in which young and older adults made prospective judgments of learning (JOLs) to monitor ongoing memory processes as well as retrospective source judgments during retrieval. The emotional valence of words (positive, negative, and neutral) served as an intrinsic cue across experiments. Extrinsic importance cues were manipulated via item-based directed forgetting cues (to-be-remembered versus to-be-forgotten cues) in Experiment 1 and value-based cues (+10 versus -10 cues) in Experiment 2. Results provide novel evidence for age-related similarity in use of extrinsic and intrinsic cues during prospective memory monitoring via JOLs. By contrast, during retrospective source monitoring, older but not young adults showed a bias to attribute positive items to extrinsic cues with higher importance, even when those attributions were inaccurate. These findings suggest that the age-related tendency to favor positive information may lead to systematic errors in retrospective monitoring, which has implications for the credibility of older adults' source judgments when monitoring memory for emotional events. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
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Cell Rep
January 2025
Department of Biology, Boston University, Boston, MA 02215, USA; Center for Neurophotonics, Boston University, Boston, MA 02215, USA; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA; Center for Systems Neuroscience, Boston University, Boston MA 02215, USA. Electronic address:
Task learning involves learning associations between stimuli and outcomes and storing these relationships in memory. While this information can be reliably decoded from population activity, individual neurons encoding this representation can drift over time. The circuit or molecular mechanisms underlying this drift and its role in learning are unclear.
View Article and Find Full Text PDFStrahlenther Onkol
January 2025
TUM School of Medicine and Health, Department of Radiation Oncology, Technische Universität München (TUM), Klinikum rechts der Isar, Munich, Germany.
Purpose: Increasing life expectancy and advances in cancer treatment will lead to more patients needing both radiation therapy (RT) and cardiac implantable electronic devices (CIEDs). CIEDs, including pacemakers and defibrillators, are essential for managing cardiac arrhythmias and heart failure. Telemetric monitoring of CIEDs checks battery status, lead function, settings, and diagnostic data, thereby identifying software deviations or damage.
View Article and Find Full Text PDFCytometry B Clin Cytom
January 2025
Department of Pediatrics, Section of Allergy and Immunology, University of Colorado School of Medicine, Aurora, Colorado, USA.
A reduced proportion of peripheral class-switched memory B cells (CSM-B cells) is presumed to indicate ineffective germinal activity. The extent that this finding corresponds to a plausible germinal center failure pathophysiology in patients not diagnosed with CVID or hyper IgM syndrome is not known. We asked if patients with low CSM-B cells are more likely to demonstrate failure to produce serum IgA and IgG than counterparts with nonreduced class-switched memory B cell levels, regardless of diagnosis.
View Article and Find Full Text PDFJ Alzheimers Dis
January 2025
Department of Neurology and the Franke Barrow Global Neuroscience Education Center, Barrow Neurological Institute, Phoenix, AZ, USA.
Background: The aim of this study was to examine the potential added value of including neuropsychiatric symptoms (NPS) in machine learning (ML) models, along with demographic features and Alzheimer's disease (AD) biomarkers, to predict decline or non-decline in global and domain-specific cognitive scores among community-dwelling older adults.
Objective: To evaluate the impact of adding NPS to AD biomarkers on ML model accuracy in predicting cognitive decline among older adults.
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Neuroimage
January 2025
Chemical Senses and Mental Health Lab, Department of Psychology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China. Electronic address:
Previous research has revealed that the insula, pallidum, thalamus, hippocampus, middle frontal gyrus, and supplementary motor area are activated during odor memory and that the performance of olfactory working memory is affected by the verbalization of odors. However, the neural mechanisms underlying olfactory working memory and the role of verbalization in olfactory working memory are not fully understood. Twenty-nine participants were enrolled in a study to complete olfactory and visual n-back tasks using high- and low-verbalizability stimuli while undergoing fMRI imaging.
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