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Diagnostic outcomes after gluten challenge in adult patients with unconfirmed coeliac disease already on a gluten-free diet: A 20-year retrospective cohort study.
Dig Liver Dis
January 2025
Department of Internal Medicine and Therapeutics, University of Pavia, Italy; Istituti Clinici Scientifici Maugeri IRCCS, Gastroenterology Unit of Pavia Institute, Italy.
Background: In uncertain cases of coeliac disease (CD), gluten challenge (GC) may be necessary to confirm or exclude the diagnosis. However, data on diagnostic outcomes after GC are limited.
Aims: We aimed to evaluate outcomes after GC in patients with unconfirmed CD who had already started a gluten-free diet (GFD), and identify predictors of a confirmed diagnosis.
Effects of instant controlled pressure drop on amaranth phytochemicals and antioxidant capacity.
Food Chem
January 2025
School of Engineering and Sciences, Tecnologico de Monterrey, Querétaro 76130, Mexico. Electronic address:
Amaranth is a pre-Columbian staple crop used as a nutritious gluten-free grain associated with several health properties. Instant Controlled Pressure Drop (DIC) is an emerging technology used in many food industries. This study evaluates the effect of DIC treatment on amaranth.
View Article and Find Full Text PDFA new histomorphological finding in the follow-up of celiac disease: Intraepithelial lymphocyte localization is a reliable indicator of dietary compliance.
Ann Diagn Pathol
January 2025
Mardin Training and Research Hospital, Adult Gastroenterology Clinic, Mardin, Turkey.
The correlation between clinical, serological, and endoscopic findings and histological response after a gluten-free diet (GFD) is limited in adult celiac (CD) patients. This study aims to evaluate the effects of GFD on intraepithelial lymphocyte (IEL) localization by comparing the histopathological, clinical, serological, and endoscopic findings of adult CD patients. The patients (n = 131) were divided into three groups: those with good (CDgc) (n = 23) and poor (CDpc) (n = 21) GFD compliance and newly diagnosed ones (nCD) (n = 87).
View Article and Find Full Text PDFCeliac Crisis: A Life-Threatening Complication of Celiac Disease.
Middle East J Dig Dis
October 2024
Department of Pediatrics, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India.
Celiac disease (CD) is an immune-mediated enteropathy with varied systemic involvement and association with increased morbidity and mortality. Strong clinical suspicion is the key, and diagnosis is made using histopathology and serology. Though the consumption of a strict gluten-free diet can improve symptoms and limit mucosal damage, curative therapy is still lacking.
View Article and Find Full Text PDFA fundamental rheological approach to determine the optimum water absorption capacity of a model gluten-free dough system: soy flour dough.
J Sci Food Agric
January 2025
Department of Animal, Veterinary and Food Sciences, University of Idaho, Moscow, ID, USA.
Background: Determining the optimum water absorption capacity of gluten-free flours for an improved breadmaking process has been a challenge because there is no standard method. In the present study, large amplitude oscillatory shear (LAOS) tests were performed to explore the impact of different levels of added water on non-linear viscoelastic response of soy flour dough in comparison to wheat flour dough at a consistency of 500 BU.
Results: Among the LAOS parameters, large strain modulus (G') and large strain rate viscosity (η') were found to better probe the impact of added water amount on non-linear viscoelastic properties of soy flour dough.
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