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| http://dx.doi.org/10.1093/ehjcr/yty065 | DOI Listing |
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Cardiac myxomas are the most common primary intracardiac tumors and are histologically benign. However, they are potentially dangerous because of the risk of systemic embolism. Echocardiography is the key diagnostic tool for atrial myxomas, allowing for the identification of the tumor, as well as determining its location, shape, size, and connections with adjacent cardiac structures.
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Obscurin is a giant protein that coordinates diverse aspects of striated muscle physiology. Obscurin immunoglobulin domains 58/59 (Ig58/59) associate with essential sarcomeric and Ca2+ cycling proteins. To explore the pathophysiological significance of Ig58/59, we generated the Obscn-ΔIg58/59 mouse model, expressing obscurin constitutively lacking Ig58/59.
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A 40-year-old male visited our clinic for cardiac evaluation. He had palpitations for several years, but the reason was unknown. Transthoracic echocardiography revealed a hyperechoic ribbon-shaped structure that moved vigorously in the right atrium.
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