Background: Considering the increased rate of microbial resistance to antibiotics and chemical side effects of antibiotics and antiseptics used for the treatment of periodontal disease, there is a need for an alternative antimicrobial agent with fewer complications. Medicinal herbs have recently become popular as novel antimicrobial agents. This study aimed to assess the antibacterial effects of hydroalcoholic extracts of , and on .
Materials And Methods: Hydroalcoholic extracts of the three medicinal plants were obtained by the maceration technique and was cultured. Antimicrobial efficacy of the three medicinal plants was compared with that of 0.2% chlorhexidine (CHX) according to the Clinical and Laboratory Standards Institute protocol using agar disc diffusion and broth microdilution techniques. All tests were repeated three times.
Results: Hydroalcoholic extracts of all three plants had antimicrobial activity against . The minimum inhibitory concentration (MIC) of , , and was 78.1, 156.2, and 1666 μg/mL with no significant difference between them. The MIC of CHX was 3.33 μg/mL, which was significantly higher than that of B. serrata extract.
Conclusion: Given that further studies confirm other properties of these extracts and their safety in terms of cytotoxicity and mutagenicity, hydroalcoholic extracts of and may be used in mouthwashes or local delivery systems to affect periodontal biofilm.
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| http://dx.doi.org/10.4103/abr.abr_205_18 | DOI Listing |
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