An Unusual Presentation of Cytomegalovirus Infection: Generalized Edema.

Med Princ Pract

Department of Pediatrics, Turkish Republic Health Ministry, Ankara Child Health Diseases, Haematology Oncology Training and Research Hospital, Ankara, Turkey.

Published: January 2021

AI Article Synopsis

  • Cytomegalovirus (CMV) infection can, though rarely, cause protein-losing gastropathy in otherwise healthy children, leading to symptoms like nausea and abdominal pain, but sometimes manifests only as generalized edema.
  • A 5-year-old boy with no other symptoms presented with generalized edema and was found to have low albumin levels but no signs of protein loss in urine; gastrointestinal examinations revealed hypertrophic gastropathy.
  • Testing confirmed a CMV infection, and the child recovered on his own after about a week, indicating that CMV can cause protein loss symptoms without typical gastrointestinal manifestations.

Article Abstract

Objective: Cytomegalovirus (CMV) infection may rarely lead to protein-losing gastropathy that presents with nausea, vomiting, abdominal pain, and edema in immunocompetent children, but extremely rarely with only generalized edema.

Clinical Presentation And Intervention: A previously healthy 5-year-old boy presented with generalized edema without any other symptoms. He had hypoalbuminemia but no proteinuria. He was evaluated for gastrointestinal protein loss, and hypertrophic gastropathy was revealed on esophagogastroduodenoscopy. Meanwhile, CMV infection was detected by serologic tests and polymerase chain reaction in the blood. He recovered spontaneously within a week.

Conclusion: CMV-related protein-losing gastropathy may present with generalized edema without any gastrointestinal symptoms.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024873PMC
http://dx.doi.org/10.1159/000500511DOI Listing

Publication Analysis

Top Keywords

generalized edema
12
cmv infection
8
protein-losing gastropathy
8
unusual presentation
4
presentation cytomegalovirus
4
cytomegalovirus infection
4
generalized
4
infection generalized
4
edema
4
edema objective
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!