Molecular imaging of infection has evolved since its inception. This articles covers a number of infectious processes, including osteomyelitis, diabetic foot infections, periprosthetic infections, cardiovascular infections (including those due to implantable devices), abdominal infections, and fever of unknown origin. Planar, SPECT, SPECT/CT, F-FDG PET/CT, and PET/MRI are also discussed. Molecular imaging of infection is a complex topic. Knowledge of the available modalities allows the imager to select the highest-yield study to answer the clinical question.
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