Multinodular and vacuolating neuronal tumour (MVNT) of the cerebrum is a relatively new, well defined histopathological and neuroradiological entity, in many cases associated with an early adult-onset epilepsy. These lesions have an indolent course and resemble both malformative and neoplastic processes, combining a focal developmental anomaly and a low-grade tumour. Herein, we report a case of a 48-year-old female patient with left temporal lobe epilepsy associated with MVNT. In addition, a comprehensive review of all the previously published cases is provided with a focus on seizure-related cases, surgical treatment, and postoperative outcome.
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Multinodular and vacuolating posterior fossa lesions of unknown significance: a long-term observational study and literature review.
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Article Synopsis
- - MV PLUS lesions are benign brain cysts that usually do not cause symptoms but can lead to neurological issues like seizures and headaches; they are mainly found in the posterior fossa and detected through MRI scans showing high intensity on T2-FLAIR sequences.
- - A case of a 52-year-old woman with symptoms like dizziness and syncope revealed a multicystic lesion via MRI, which showed no harmful changes after treatment, highlighting the need for careful monitoring and further research.
- - These lesions pose diagnostic challenges due to their complex features; although benign, their management and pathogenesis are still being studied, stressing the importance of ongoing investigation in the field.
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