AI Article Synopsis

  • Strategic planning for hepatitis C screening and treatment relies on accurate data about how often the virus clears on its own.
  • Previous studies have reported spontaneous clearance rates of HCV between 15% and 60%.
  • This 20-year observational study aimed to assess trends in HCV spontaneous clearance and identify factors linked to viremia in HCV-antibody-positive patients to better predict treatment needs.

Article Abstract

Strategic planning for hepatitis C virus (HCV) screening and treatment requires up-to-date information on the prevalence of HCV spontaneous clearance. Published estimates of HCV spontaneous clearance range from 15% to 60%. We conducted an observational study over 20 years to evaluate trends in the prevalence of HCV spontaneous clearance. Our goals were to estimate the proportion of HCV-antibody-positive patients who were viremic, and to identify factors associated with viremia, thus facilitating prediction of the number of patients needing treatment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801008PMC
http://dx.doi.org/10.1016/j.cgh.2019.04.035DOI Listing

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