AI Article Synopsis
- The HAVOC score was created to estimate the risk of atrial fibrillation (AF) after a cryptogenic stroke or transient ischemic attack, and this study aimed to test its effectiveness in patients from the CRYSTAL AF study who received insertable cardiac monitors (ICMs).
- In the analysis, 214 patients were monitored for AF detection over 12 months, revealing that 40 patients were diagnosed with AF, and those with AF had a higher median HAVOC score compared to those without AF.
- The study concluded that the HAVOC score effectively stratifies AF risk in patients post-stroke or TIA, highlighting the importance of various risk factors beyond traditional ones.
Article Abstract
Background: The HAVOC score was previously developed to predict the risk of atrial fibrillation (AF) after cryptogenic stroke (CS) or transient ischemic attack (TIA). The purpose of this study was to apply the HAVOC score to patients who received insertable cardiac monitors (ICMs) in the CRYSTAL AF study.
Methods: All patients from the CRYSTAL AF study who received an ICM were included. HAVOC score (one point each for peripheral vascular disease and obesity with body mass index >30, two points each for hypertension, age ⩾ 75, valvular heart disease, and coronary artery disease, 4 points for congestive heart failure) was computed for all patients. The primary endpoint was AF detection by 12 months of ICM monitoring.
Results: A total of 214 patients who received ICM were included. AF was detected in 40 patients while the remaining 174 patients were AF negative. The HAVOC score was significantly higher among patients with AF [median 3.0 with interquartile range (IQR) 2-4] than those without AF [median 2.0 (IQR 0-3)], = 0.01. AF increased significantly across the three HAVOC score groups: 11% in Group A (score 0-1), 18% in Group B (score 2-3), and 32 % in Group C (score ⩾ 4) with = 0.02.
Conclusions: The HAVOC score was shown in this post hoc analysis of CRYSTAL AF to successfully stratify AF risk post CS or TIA. The 11% AF rate in the lowest HAVOC score group highlights the significance of nontraditional contributors to AF and ischemic stroke.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460885 | PMC |
| http://dx.doi.org/10.1177/1756286419842698 | DOI Listing |
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