Johne's disease is chronic enteric incurable disease in ruminant, is caused by Mycobacterium avium subsp. paratuberculosis (MAP). The data about incidence and economic importance of the disease in Egypt are scare. The present study investigated the prevalence of Johne`s disease among cattle in some localities in Egypt. The results revealed that the infection was significantly higher in older animals than young animals (P = <0.05). The prevalence of the disease was higher in Gharbia governorate (19.6%) in comparison with other studied area. To determine the efficiency of diagnostic tests, 138 fecal samples were examined by culture and real-time PCR, the result showed slight agreement between both tests for detection of MAP in feces. Sequence analysis of IS1311 gene for isolated MAP strain from Egypt revealed high identity (98%) with other MAP strains from Germany and Netherland. MAP belongs to a subspecies genetically different from Mycobacterium avium subsp. Hominissuis (MAH) and Mycobacterium avium subsp. avium (MAA), therefore these results are as would be expected. This study confirms the circulation of MAP among cattle in Egypt and highlights the need for more study on the disease in the Middle East.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.actatropica.2019.04.019 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Whole-genome phylogenetic analysis of complex from clinical respiratory samples.
Microbiol Spectr
January 2025
Department of Laboratory Medicine, National University Hospital, Singapore, Singapore.
Unlabelled: The complex (MAC) is a common causative agent causing nontuberculous mycobacterial (NTM) pulmonary disease worldwide. Whole-genome sequencing was performed on a total of 203 retrospective MAC isolates from respiratory specimens. Phylogenomic analysis identified eight subspecies and species.
View Article and Find Full Text PDFBayesian estimation of diagnostic accuracy of fecal smears, fecal PCR and serum ELISA for detecting Mycobacterium avium subsp. paratuberculosis infections in four domestic ruminant species in Saudi Arabia.
Vet Microbiol
January 2025
Département de pathologie et microbiologie, Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec, Canada; Research Chair in Biosecurity of Dairy Production, Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec, Canada.
Paratuberculosis, a chronic wasting disease affecting domestic and wild ruminants worldwide, is caused by Mycobacterium avium subsp. paratuberculosis (MAP). Various diagnostic tests exist for detecting MAP infection; however, none of them possess perfect accuracy to be qualified as a reference standard test, particularly due to their notably low sensitivity.
View Article and Find Full Text PDFThe Impact of subsp. on Intestinal Microbial Community Composition and Diversity in Small-Tail Han Sheep.
Pathogens
December 2024
College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot 010010, China.
Paratuberculosis (PTB), primarily caused by subsp. (MAP), is a chronic infection that affects ruminants and is difficult to prevent, diagnose, and treat. Investigating how MAP infections affect the gut microbiota in sheep can aid in the prevention and treatment of ovine PTB.
View Article and Find Full Text PDFEnhancing Inner Area Revaluation Through Optional Control Programmes for Infectious Bovine Rhinotracheitis and Ruminant Paratuberculosis Potentially Linked to Crohn's Disease in Humans.
Int J Environ Res Public Health
November 2024
Department of Agricultural, Environmental and Food Sciences (DiAAA), University of Molise, Via Francesco de Sanctis snc, 86100 Campobasso, Italy.
Regulation (EU) 2016/429 introduces comprehensive guidelines for managing transmissible animal diseases, including zoonoses. The subsequent Commission Implementing Regulation 2018/1882 categorizes these diseases into five groups, each with specific responses, ranging from mandatory eradication to optional eradication or surveillance. Key regulatory priorities include enhanced animal traceability, biosecurity, wildlife pathogen control, sustainable farming practices, and minimizing the impact of diseases on public health, animal health, and the environment.
View Article and Find Full Text PDFUse of a hidden Markov model for interpretation of serial cow milk paratuberculosis antibody enzyme-linked immunosorbent assay results adjusted for milk yield and quality.
Prev Vet Med
December 2024
School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Leicestershire LE12 5RD, United Kingdom.
Paratuberculosis (Johne's disease), caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a common, economically-important and potentially zoonotic contagious disease of cattle, with worldwide distribution. Disease management relies on identification of animals which are at high-risk of being infected or infectious.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!