AI Article Synopsis

  • Researchers discovered a new picornavirus in young lambs that showed neurological symptoms and brain inflammation during studies in the UK from 2016 to 2017.
  • The virus was found to specifically target neurons, as shown by in situ hybridization techniques.
  • Additionally, the virus was detected in older samples from similar cases in lambs dating back to 1998-2014, indicating a longer history of this infection.

Article Abstract

Using metagenomic analysis, we identified a novel picornavirus in young preweaned lambs with neurologic signs associated with severe nonsuppurative encephalitis and sensory ganglionitis in 2016 and 2017 in the United Kingdom. In situ hybridization demonstrated intralesional neuronotropism of this virus, which was also detected in archived samples of similarly affected lambs (1998-2014).

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478204PMC
http://dx.doi.org/10.3201/eid2505.181573DOI Listing

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