We report the rapid development of a myasthenic crisis as the first-time manifestation of myasthenia gravis. The symptoms developed in the course of acute leptospirosis associated with a new sequence type of Leptospira interrogans. Antibiotic treatment led to rapid amelioration of myasthenia.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478190PMC
http://dx.doi.org/10.3201/eid2505.181591DOI Listing

Publication Analysis

Top Keywords

leptospirosis associated
8
associated sequence
8
sequence type
8
type leptospira
8
leptospira interrogans
8
severe myasthenic
4
myasthenic manifestation
4
manifestation leptospirosis
4
interrogans report
4
report rapid
4

Similar Publications

This study aimed to identify and compare risk factors associated with canine leptospirosis and Leptospira seropositivity in New South Wales, Australia. Seventy-nine canine cases of confirmed leptospirosis (clinical cases) and 16 healthy dogs seropositive to Leptospira (seropositive cases) were included in the study; these were separately compared to 394 healthy dogs seronegative to Leptospira (controls) in at-risk areas. A questionnaire investigated rat contact, stagnant water, dog park access and household number of dogs and cats.

View Article and Find Full Text PDF

Background: Leptospirosis is a widespread zoonosis caused by bacteria in the genus Leptospira. Basic epidemiological information is crucial to mitigating disease risk but is lacking for leptospirosis; notably, the hosts responsible for maintaining Leptospira remain largely unknown. Frequently observed near human habitations, hedgehogs (Erinaceus europaeus) are taken to wildlife rescue centres when found sick or injured.

View Article and Find Full Text PDF

Leptospira spp. is recognized by TLR2 and induces IFN-β and IFN-λ expression in smegma from naturally infected bulls.

Comp Immunol Microbiol Infect Dis

December 2024

Instituto de Investigaciones en Producción, Sanidad y Ambiente - IIPROSAM (CONICET-UNMdP). Facultad de Ciencias Exactas y Naturales-UNMdP Centro Científico Tecnológico Mar del Plata-CONICET Centro de Asociación Simple CIC-PBA, Mar del Plata, Buenos Aires, Argentina. Electronic address:

Leptospirosis, a zoonosis with a wide worldwide distribution, causes significant reproductive losses in cattle. The genital presentation of the disease has been reported, and its understanding is crucial for the implementation of adequate sanitary measures. Although Leptospira spp.

View Article and Find Full Text PDF

The Relationship Between the Spatial Occurrence of Exposed Animals and the Characteristics of the Peridomiciles They Inhabit in a Locality of Southeastern Mexico.

Pathogens

November 2024

Laboratorio de Zoonosis y otras Enfermedades Transmitidas por Vector, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi", Universidad Autónoma de Yucatán, Mérida 97000, Yucatán, Mexico.

The occurrence of in mammals is an indicator for assessing potential health risks, particularly in tropical regions. Understanding their hosts' habitat characteristics and spatial occurrence is essential to surveil them. This study aimed to determine the characteristics of the peridomiciles associated with the spatial occurrence of hosts.

View Article and Find Full Text PDF
Article Synopsis
  • The study examined the causes and outcomes of acute kidney injury (AKI) in 464 patients at a tertiary care center in Sri Lanka, highlighting the influence of age, comorbidities, and severity on patient prognosis.
  • Of the patients, 56.5% were male, with a mean age of 57.04 years; by 90 days, most patients showed improvement in renal function, though mortality rates were highest in those over 60 and with more severe AKI.
  • The research identified major challenges in AKI management, including inadequate resources and infrastructure, underscoring the importance of early identification and intervention for at-risk populations.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!