Background: Highly porous metaphyseal cones have been introduced to restore metaphyseal integrity for improved cement interdigitation to achieve durable fixation in revision total knee arthroplasty (TKA). The purpose of this study is to review the survivorship, clinical results, and complications of revision TKA using highly porous 3-dimensionally printed titanium metaphyseal cones.
Methods: This is a review of 62 revision TKAs using metaphyseal tibial cones, with 15 cases utilizing both tibial and femoral cones. The mean age of the patients was 66 years (range 32-84) who had a mean follow-up of 27 months (range 24-34). There were 38 women and 24 men, who had a mean body mass index of 33 (range 18.3-62).
Results: Revision-free survival of the cones was 90.2%. If infection was excluded, survivorship was 100%. There were no cases of aseptic loosening. The mean Knee Society Score improved from 51 points preoperatively to 80 points at the time of latest follow-up. The mean Knee Society Functional Score improved from 48 points preoperatively to 68 points. A total of 15 of the 62 patients (24%) required additional surgery: 10 (16%) for infection, 3 (5%) for contracture, 1 for patellar subluxation, and 1 for quadriceps tendon rupture.
Conclusion: Metaphyseal fixation is important for survivorship in revision TKA which can be challenging due to cancellous and structural bone loss encountered at the time of revision. Prosthetic joint infection continues to be the leading cause of failure in revision TKA. The use of highly porous titanium metaphyseal cones produced from 3-dimensionally printed technology used in this study demonstrated excellent short-term results with no cases of aseptic loosening. Further follow-up is required to determine if these results can be durable over a longer period.
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http://dx.doi.org/10.1016/j.arth.2019.03.045 | DOI Listing |
In Vitro Model
February 2024
Faculty of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-Cho, Koganei, Tokyo 184-8588 Japan.
Unlabelled: Engineered three-dimensional (3D) tissue culture platforms are useful for reproducing and elucidating complex in vivo biological phenomena. Spheroids, 3D aggregates of living cells, are produced based on physicochemical or microfabrication technologies and are commonly used even in cancer pathology research. However, conventional methods have difficulties in constructing 3D structures depending on the cell types, and require specialized techniques/lab know-how to reproducibly control the spheroid size and shape.
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January 2025
College of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha, 410004, China.
3D porous carbon electrodes have attracted significant attention for advancing compressible supercapacitors (SCs) in flexible electronics. The micro- and nanoscale architecture critically influences the mechanical and electrochemical performance of these electrodes. However, achieving a balance between high compressive strength, electrochemical stability, and cost-effective sustainable production remains challenging.
View Article and Find Full Text PDFBiofabrication
January 2025
Biomedical Engineering Department, Technion Israel Institute of Technology, Technion City, Haifa 32000, Haifa, Haifa, 3200003, ISRAEL.
Best cosmetic outcomes of breast reconstruction using tissue engineering techniques rely on the scaffold architecture and material, which are currently both to be determined. This study suggests an approach for a rational design of breast-shaped scaffold architecture, in which structural analysis is implemented to predict its stiffness and adjust it to that of the native tissue. This approach can help achieve the goal of optimal scaffold architecture for breast tissue engineering.
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January 2025
Frontiers Science Center for New Organic Matter, Key Laboratory of Advanced Energy Materials Chemistry (MOE), College of Chemistry, Nankai University, Tianjin 300071, China.
The fixation of carbon dioxide (CO) directly from flue gas into valuable chemicals like 2-oxazolidinones is of great significance for economic and environmental benefits, which is typically catalyzed by noble-metal catalysts and under harsh conditions. Herein, a novel 2-fold interpenetrated framework {[Co(μ-O)(TCA)(HDPTA)]·2HO·2DMF} [Co(II)-based metal-organic framework ()] containing [Co] clusters and highly dense amino groups (-NH) dispersed in the channel was prepared, exhibiting high solvent/pH stability and CO adsorption capacity (24.9 cm·g).
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
School of Chemistry and Chemical Engineering, Guangxi University, 100 East University Road, Nanning 530004, PR China. Electronic address:
Cinnamaldehyde (CIN) is gaining interest as a highly effective natural antimicrobial agent to extend the shelf life of fruits. However, its inherent instability limits further applications. In this work, a new strategy for the synthesis of HKUST-1 to encapsulate CINs by in situ growth method using copper-ammonia fiber as precursors is proposed.
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