Background And Objective: To quantify vessel tortuosity among infants with retinopathy of prematurity (ROP).

Patients And Methods: This was a retrospective study including 61 RetCam images from 33 infants. The laser treatment (LT) group included 17 infants who underwent laser for ROP. The no-treatment (NT) group included 16 infants. The modified ROPtool was used to calculate mean vessel tortuosity (MVT) and highest vessel tortuosity (HVT) for the participants and for the standard plus disease photograph from the Early Treatment for Retinopathy of Prematurity (ETROP) study.

Results: The median MVT was 1.226 versus 1.056 for the LT and NT groups, respectively (P < .001). The median HVT was 1.346 versus 1.088 (P < .001). An MVT of 1.124 was 96.7% sensitive and 100% specific for identifying infants with treatment-requiring ROP. Both MVT and HVT cutoff values correctly captured plus disease in the standard ETROP trial photograph.

Conclusion: The modified ROPtool can be used to identify infants who have treatment-requiring ROP with a high level of sensitivity and specificity. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:215-220.].

Download full-text PDF

Source
http://dx.doi.org/10.3928/23258160-20190401-03DOI Listing

Publication Analysis

Top Keywords

vessel tortuosity
16
modified roptool
12
retinopathy prematurity
12
cutoff values
8
treatment retinopathy
8
group included
8
included infants
8
infants treatment-requiring
8
treatment-requiring rop
8
infants
6

Similar Publications

Carotid artery stenosis is a significant cause of ischemic stroke, often necessitating interventions like carotid artery stenting (CAS) to restore adequate blood flow. However, complications like intraprocedural arterial dissection can arise during the procedure. This report presents a case of intraprocedural arterial dissection during CAS using a CASPER Rx stent.

View Article and Find Full Text PDF

Background: Severe vessel tortuosity may prevent a microcatheter from reaching a distal vessel. However, the Double-Wire Technique (DWT) may facilitate the procedure. The present study evaluated the feasibility and safety of guiding a 0.

View Article and Find Full Text PDF

Comparison of retinal vascular abnormalities in the fellow eyes of children with Coats' disease and normal subjects using ultra-widefield fundus fluorescein angiography.

Photodiagnosis Photodyn Ther

December 2024

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China; Beijing Ophthalmology and Visual Science Key Laboratory, Beijing 100730, China. Electronic address:

Purpose: To investigate retinal vascular abnormalities in the affected and fellow eyes of children with Coats' disease using Optos® ultra-widefield fundus fluorescein angiography (UWFFA) and compare the peripheral vascular abnormalities between fellow eyes and normal control eyes.

Methods: Children diagnosed with Coats' disease who underwent UWFFA were retrospectively reviewed. Healthy eyes with complete UWFFA data were selected as controls.

View Article and Find Full Text PDF

Use of nailfold capillaroscopy for the assessment of patients undergoing digit replantation and revascularization.

Jt Dis Relat Surg

January 2025

İnönü Üniversitesi Tıp Fakültesi Turgut Özal Tıp Merkezi, Ortopedi ve Travmatoloji Anabilim Dalı, 44280 Malatya, Türkiye.

Objectives: In this study, we aimed to evaluate microvascular changes using nailfold capillaroscopy in patients who underwent digit replantation and revascularization.

Patients And Methods: A total of 46 patients (34 males, 12 females; mean age: 45.8±17.

View Article and Find Full Text PDF

Skin layer-specific spatiotemporal assessment of micrometabolism during wound angiogenesis.

Commun Biol

December 2024

Institute for Biomedical Engineering and Institute of Pharmacology and Toxicology, Faculty of Medicine, University of Zurich, 8057, Zurich, Switzerland.

Proper oxygen delivery through the microvasculature to injury site is essential to ensure the metabolic cascade during wound healing. Adaptation of vascular structure and oxygenation is key to unravel the regulation of blood perfusion, oxygen distribution and new tissue formation. Yet, visualizing micrometabolic responses at large scale in unperturbed living tissue remains challenging.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!