Filamentous fungi perform tremendously in adsorption of dyes from polluted environment. In this study, LAG decolorized thiazole yellow G dye within 5 days. Scale up studies done revealed that maximum decolorization (98%) was achieved at a concentration (10 mg L), temperature (35 °C) and pH 6. The fungus exhibited significant inductions in laccase (71%) and lignin peroxidase (48%) respectively. Spectrometric analysis (UV-vis, HPLC and gas chromatography-mass spectrometry) was used in analyzing the degraded products of the dye. The GCMS analysis revealed the production of two metabolites; sodium 6-methyl-2-phenyl-1,3-benzothiazole-7-sulfonate and 2-phenyl-4,5-dihydro-1,3-thiazole after degradation of thiazole yellow G dye. A metabolic pathway of thiazole yellow G dye degradation by was proposed. Significant growth in plumule and radicle couple with an attendant increase in germination further confirmed the detoxified status of the dye after degradation.
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http://dx.doi.org/10.1016/j.btre.2019.e00327 | DOI Listing |
PLoS One
December 2024
The Affiliated Changsha Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Nirmatrelvir/Ritonavir, acting as an effective agent against COVID-19, has achieved considerable results in clinical studies in terms of drug efficacy. However, there is little research about its medication safety. Based on the FDA adverse event reporting system (FAERS) database, this study aims to mine the adverse reaction signals of the latest major recommended drug Nirmatrelvir/Ritonavir for the antiviral treatment of COVID-19, so as to provide a basis for safe and rational drug use.
View Article and Find Full Text PDFSci Rep
November 2024
Laser Laboratory, Physics Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt.
The optical, photoluminescence, and electrical properties of Poly(Z)-PTI and Poly(E)-PTI, two Poly-Pyrrol-Thiazol-Imine polymers with comparable chemical structures but distinct configurations, were examined. Using the dip-casting method, polymer films were deposited on ITO substrates. UV-VIS spectroscopy revealed that both polymers diverged between 500 and 800 nm, showing the impact of molecular arrangement, but showed similar absorption behavior for wavelengths shorter than 500 nm.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
February 2025
Department of Chemistry, Morgan State University, 1700 E Cold Spring Ln, Baltimore, MD 21251 USA. Electronic address:
A new sensor based on Ethylbenzothiazolium-2-hydroxynaphthaldehyde conjugate-based fluorescent sensor, (E)-3-ethyl-2-(2-(2-hydroxynaphthalen-1-yl) vinyl) benzo[d]thiazol-3-ium iodide (SU-1) was designed and synthesized. The structure of SU-1 was confirmed by H NMR, C NMR, HRMS, and single crystal XRD spectral analysis. SU-1 displayed a colorimetric and fluorometric response in a DMSO:HO (1:1,v/v) matrix, changing color from pale yellow to colorless visible to the naked eye, accompanied by a ∼ 120 nm red-shift in the absorption spectra upon CN addition.
View Article and Find Full Text PDFJ Inorg Biochem
January 2025
State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Laboratory for Marine Drugs and Bioproducts, Qingdao Marine Science and Technology Center, Qingdao 266237, China. Electronic address:
A novel artificial peroxidase has been developed for the efficient degradation of the non-steroidal anti-inflammatory drug meloxicam by combining computer simulation and genetic engineering techniques. The results showed that the artificial peroxidase was able to completely degrade meloxicam within 90 s, with a degradation rate of 100 %, which was much higher than that of natural lacquer (46 %). The reaction time of the artificial enzyme was significantly shorter than that of natural peroxidase (10 min) and laccase (48 h).
View Article and Find Full Text PDFFood Chem
January 2025
College of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, PR China. Electronic address:
In this study, we focused on the successful construction of [(4,4'-bipy/PMoCo)] modified electrodes using the layer-by-layer assembly method for the sensitive detection of sulfathiazole (ST). The redox reaction between ST and the metal ions in the modified layer leads to the transfer of electrons, resulting in the generation of the electrical signal. The introduction of 4,4'-bipyridine (4,4'-bipy) enhanced the molecular recognition of ST by the modified electrode.
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