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In this present study, we conducted untargeted metabolic profiling using gas chromatography-mass spectrometry (GC-MS) analysis of ascidian to assess the chemical constituents by searching in NIST library with promising biological properties against anti-bacterial and Zika virus vector mosquitocidal properties. Metabolites, steroids and fatty acids are abundant in crude compounds of ascidian and showed potential zone growth inhibition against bacterial strains (10 mm). The active crude compounds of exhibited prominent larvicidal activity against the Zika vector mosquitoes of (LC values of 0.44 mg/ml) and (LC values of 2.23 mg/ml). The findings of this study provide a first evidence of the biological properties exhibited by extracts, thus increasing the knowledge about the Zika virus vector mosquitocidal properties of ascidian. Overall, ascidian is promising and biocontrol or eco-friendly tool against and with prospective toxicity against non-target organisms.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456632 | PMC |
| http://dx.doi.org/10.1007/s13205-019-1699-3 | DOI Listing |
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