The iron oxide-based anode materials are widely studied and reported due to their abundance, low cost, high energy density and environmental friendliness for lithium ion batteries (LIBs). However, the application of LIBs is always limited by the poor rate capability and stability. In order to tackle these issues, a novel material with carbon-encapsulated FeO nanorods stuck together by multilevel porous carbon (FeO@C/PC) is prepared through directly carbonizing the Fe-based metal-organic framework under a nitrogen atmosphere. This novel material shows a high specific capacity and rate performance. The initial specific capacity can reach 1789 mAh g at a current density of 0.1 A g, and the specific capacity still remains 1105.3 mAh g and 783.5 mAh g after 150 cycles at the current densities of 0.1 A g and 1 A g, respectively. Even under a current density as high as 12 A g, the specific capacity can achieve 309 mAh g after 2000 cycles with an average attenuation rate of 0.019% per cycle. Overall, the simple strategy, low cost and high capacity can make the practical application possible.
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http://dx.doi.org/10.1088/1361-6528/ab1a83 | DOI Listing |
Phys Chem Chem Phys
January 2025
School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia QLD 4072, Australia.
Steroids are organic compounds found in all forms of biological life. Besides their structural roles in cell membranes, steroids act as signalling molecules in various physiological processes and are used to treat inflammatory conditions. It has been hypothesised that in addition to their well-characterised genomic and non-genomic pathways, steroids exert their biological or pharmacological activities an indirect, nonreceptor-mediated membrane mechanism caused by steroid-induced changes to the physicochemical properties of cell membranes.
View Article and Find Full Text PDFBiochemistry
January 2025
Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
1-Deoxy-d-xylulose 5-phosphate synthase (DXPS) is a unique thiamin diphosphate (ThDP)-dependent enzyme that catalyzes the formation of DXP, a branchpoint metabolite required for the biosynthesis of vitamins and isoprenoids in bacterial pathogens. DXPS has relaxed substrate specificity and utilizes a gated mechanism, equipping DXPS to sense and respond to diverse substrates. We speculate that pathogens utilize this distinct gated mechanism in different ways to support metabolic adaptation during infection.
View Article and Find Full Text PDFTherapies against hematological malignancies using chimeric antigen receptors (CAR)-T cells have shown great potential; however, therapeutic success in solid tumors has been constrained due to limited tumor trafficking and infiltration, as well as the scarcity of cancer-specific solid tumor antigens. Therefore, the enrichment of tumor-antigen specific CAR-T cells in the desired region is critical for improving therapy efficacy and reducing systemic on-target/off-tumor side effects. Here, we functionalized human CAR-T cells with superparamagnetic iron oxide nanoparticles (SPIONs), making them magnetically controllable for site-directed targeting.
View Article and Find Full Text PDFFront Nutr
December 2024
College of Horticulture, Xinjiang Agricultural University, Urumqi, China.
The application of plant growth regulators is an effective method to enhance flavonoid content in certain fruits; however, there is limited research comparing the effects of different plant growth regulators. This study evaluated the impact of pre-harvest application with melatonin, 24-epibrassinolide, and methyl jasmonate on flavonoid content in blueberry fruit. All three plant growth regulators increased the total polyphenol content, total flavonoid content, antioxidant capacities, and the activities of key enzymes involved in flavonoid biosynthesis, including flavone synthase, flavanone 3-hydroxylase, flavonol synthase, anthocyanidin synthase, and leucoanthocyanidin reductase.
View Article and Find Full Text PDFUnlabelled: Members of the gut microbiome encounter a barrage of host- and microbe-derived microbiocidal factors that must be overcome to maintain fitness in the intestine. The long-term stability of many gut microbiome strains within the microbiome suggests the existence of strain-specific strategies that have evolved to foster resilience to such insults. Despite this, little is known about the mechanisms that mediate this resistance.
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